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398160

Sigma-Aldrich

Hexamethylenetetramine

ACS reagent, ≥99.0%

Synonym(s):

1,3,5,7-Tetraazatricyclo[3.3.1.13,7]decane, Hexamine, Methenamine, Urotropine

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Estimated to ship onJanuary 27, 2026


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5 G
$38.40
250 G
$44.00
1 KG
$111.00

About This Item

Empirical Formula (Hill Notation):
C6H12N4
CAS Number:
Molecular Weight:
140.19
Beilstein/REAXYS Number:
2018
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.21
form:
solid
assay:
≥99.0%

$38.40


Estimated to ship onJanuary 27, 2026


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grade

ACS reagent

Quality Level

vapor pressure

<0.01 mmHg ( 20 °C)

assay

≥99.0%

form

solid

autoignition temp.

770 °F

ign. residue

≤0.1%

loss

≤2.0% loss on drying

mp

280 °C (subl.) (lit.)

solubility

water: soluble

cation traces

heavy metals: ≤0.001% (by ICP)

SMILES string

C1N2CN3CN1CN(C2)C3

InChI

1S/C6H12N4/c1-7-2-9-4-8(1)5-10(3-7)6-9/h1-6H2

InChI key

VKYKSIONXSXAKP-UHFFFAOYSA-N

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General description

Hexamethylenetetramine (HMTA) is a water soluble, heterocyclic organic compound with a cage-like structure resembling adamantane.[1] It is commonly used in treating urinary tract infection.[2]

Application

Hexamethylenetetramine (HMTA) may be used as:
  • Raw material in the synthesis of blue emitting boron carbon oxynitride (BCNO) phosphors[3] and Zinc oxide (ZnO) nanorods.[4]
  • Catalyst in the synthesis of 2-amino-4H-pyran derivatives.[1]
  • Surfactant in the synthesis of HMTA capped transition metals doped ZnS nanoparticles.[5]
  • Precipitant and template in the synthesis of Ni(OH)2.[6]

Legal Information

Redi-Dri is a trademark of Sigma-Aldrich Co. LLC

pictograms

FlameExclamation mark

signalword

Warning

hcodes

Hazard Classifications

Flam. Sol. 2 - Skin Sens. 1B

Storage Class

4.1B - Flammable solid hazardous materials

wgk_germany

WGK 1

flash_point_f

482.0 °F - closed cup

flash_point_c

250 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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Preparation of NiO Microspheres by Hydrothermal Method and its Electrochemical Capacitive Properties.
Li QQ, et al.
Materials Science Forum, 814, 81-85 (2015)
Blue emitting BCNO phosphors with high quantum yields.
Zhang X, et al.
Journal of Material Chemistry C, 3(14), 3311-3317 (2015)
Controlling Diameter, Length and Characterization of ZnO Nanorods by Simple Hydrothermal Method for Solar Cells.
Kurda AH, et al.
World Journal of Nano Science and Engineering, 5(1), 34-34 (2015)
Hexamethylenetetramine as an Efficient Catalyst for One Pot, Three Component Synthesis of 2-Amino-4H-Pyran Derivatives.
Beheshtiha SY, et al.
Chemical Science Transactions, 4(3) (2015)
Methenamine in dairy products by isotope dilution gas chromatography coupled with triple quadrupole mass spectrometry: Method validation and occurrence.
Xu X, et al.
Food Control, 57, 89-95 (2015)

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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