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32446

Sigma-Aldrich

3,3′-Diethyloxadicarbocyanine iodide

for fluorescence, ≥99.0% (HPLC)

Synonym(s):

3-Ethyl-2-[5-(3-ethyl-2-benzoxazolinylidene)-1,3-pentadienyl]benzoxazolium iodide, DODC Iodide

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About This Item

Empirical Formula (Hill Notation):
C23H23IN2O2
CAS Number:
Molecular Weight:
486.35
Beilstein/REAXYS Number:
3838937
EC Number:
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:

grade

for fluorescence

assay

≥99.0% (HPLC)

mp

232 °C (dec.) (lit.)

solubility

DMF: soluble
methanol: soluble

fluorescence

λex 579 nm; λem 610 nm in methanol

storage temp.

2-8°C

SMILES string

[I-].CCN1\C(Oc2ccccc12)=C\C=C\C=C\c3oc4ccccc4[n+]3CC

InChI

1S/C23H23N2O2.HI/c1-3-24-18-12-8-10-14-20(18)26-22(24)16-6-5-7-17-23-25(4-2)19-13-9-11-15-21(19)27-23;/h5-17H,3-4H2,1-2H3;1H/q+1;/p-1

Inchi Key

CLDZYSUDOQXJOU-UHFFFAOYSA-M

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Other Notes

Potential sensitive probe. Staining of living presynaptic nerve terminals[1]; Relationship between membrane potential and calcium ion fluxes in isolated sarcoplasmic reticulum vesicles[2]

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The relationship between membrane potential and Ca2+ fluxes in isolated sarcoplasmic reticulum vesicles.
T Beeler et al.
FEBS letters, 98(1), 173-176 (1979-02-01)
D Yoshikami et al.
Nature, 310(5972), 53-56 (1984-07-05)
Johnson et al. have recently shown that several positively charged, membrane-permeant fluorescent dyes can serve as vital stains for mitochondria in cultured cells. We report here that presynaptic nerve terminals, which are characteristically rich in mitochondria, can also be vitally

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