32173
Ipronidazole
VETRANAL®, analytical standard
Synonym(s):
1-Methyl-2-(1-methylethyl)-5-nitro-1H-imidazole, 2-Isopropyl-1-methyl-5-nitroimidazol, NSC 109212, Ro 07-1554
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About This Item
Empirical Formula (Hill Notation):
C7H11N3O2
CAS Number:
Molecular Weight:
169.18
Beilstein/REAXYS Number:
744577
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24
Recommended Products
grade
analytical standard
Quality Level
product line
VETRANAL®
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
forensics and toxicology
veterinary
format
neat
InChI
1S/C7H11N3O2/c1-5(2)7-8-4-6(9(7)3)10(11)12/h4-5H,1-3H3
InChI key
NTAFJUSDNOSFFY-UHFFFAOYSA-N
General description
Ipronidazole is a veterinary drug, which is widely used in controlling histomoniasis in turkeys.
Application
Ipronidazole may be used as a reference standard in the determination of ipronidazole in tissue samples using high-performance liquid chromatography coupled with an ultraviolet detector (HPLC) and thermospray tandem mass spectrometry (HPLC-MS/MS).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
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Legal Information
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
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A major rat faecal metabolite of ipronidazole.
G Weiss et al.
Xenobiotica; the fate of foreign compounds in biological systems, 11(3), 207-215 (1981-03-01)
E G Schildknecht et al.
Parasitology, 78(1), 19-31 (1979-02-01)
Vitamins A, E and K were incorporated into turkey starter rations at normal (1 x ), 5 x and 50 x the National Research Council recommended vitamin levels and evaluated for their effect on histomoniasis in turkeys. Infected as well
Treatment of trichomoniasis.
O J Williams et al.
Australian veterinary journal, 64(5), 159-160 (1987-05-01)
B Abbitt et al.
Journal of the American Veterinary Medical Association, 188(1), 67-69 (1986-01-01)
Two of 3 adult Greyhounds with clinical signs of giardiasis were treated by the addition of ipronidazole hydrochloride to their water supply (126 mg/L) for 7 days. Within 15 hours, the dogs had improved clinically, and large numbers of degenerating
J E Roybal et al.
Journal - Association of Official Analytical Chemists, 70(4), 626-630 (1987-07-01)
A simple and rapid method is described for the determination of dimetridazole (DMZ) and ipronidazole (IPR) in swine feeds at various levels (0.11-110 ppm). The drugs are released from feed by prewetting with a buffer, followed by extraction with either
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