320536

Thionyl chloride

reagent grade, 97%

• Linear Formula: SOCl₂
• CAS Number: 7719-09-7
• Molecular Weight: 118.97
• Beilstein/REAXYS Number: 1209273
• EC Number: 231-748-8
• MDL number: MFCD00011449
• UNSPSC Code: 12352300
• PubChem Substance ID: 24859269
• NACRES: NA.21

Properties

• grade: reagent grade
• Quality Level: 100
• vapor pressure: 97 mmHg ( 20 °C)
• assay: 97%
• form: liquid
• refractive index: n20/D 1.518 (lit.)
• bp: 79 °C (lit.)
• mp: −105 °C (lit.)
• density: 1.631 g/mL at 25 °C (lit.)
• SMILES string: ClS(Cl)=O
• InChI: 1S/Cl2OS/c1-4(2)3
• InChI key: FYSNRJHAOHDILO-UHFFFAOYSA-N

Description

General description

Thionyl chloride is an inorganic acid chloride mainly used as a reagent to prepare carboxylic acid chlorides from carboxylic acids.

Application

Thionyl chloride may be used in the following processes:

• To facilitate the synthesis of indenones from 3-hydroxyindanones via dehydroxylation.
• To functionalize silica gel for thioacetalization of aldehydes.
• Conversion of tert-butyl esters to acid chlorides.
• Conversion of aliphatic and aromatic sulfoxides to sulfides in the presence of triphenylphosphine.

Safety Information

• pictograms: GHS06,GHS05
• signalword: Danger
• hcodes: H302,H314,H331,H335
• pcodes: P261 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1A - STOT SE 3
• target_organs: Respiratory system
• supp_hazards: EUH014,EUH029
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter