31736

Sulfadoxin

VETRANAL^®, analytical standard

• Synonym(s): 4-Amino-N-(5,6-dimethoxy-4-pyrimidinyl)benzenesulfonamide, Sulfadoxine
• Empirical Formula (Hill Notation): C₁₂H₁₄N₄O₄S
• CAS Number: 2447-57-6
• Molecular Weight: 310.33
• Beilstein/REAXYS Number: 625453
• EC Number: 219-504-9
• MDL number: MFCD00792890
• UNSPSC Code: 41116107
• PubChem Substance ID: 329753909
• NACRES: NA.24

Properties

• grade: analytical standard
• Quality Level: 100
• product line: VETRANAL^®
• shelf life: limited shelf life, expiry date on the label
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• application(s): clinical testing
• format: neat
• storage temp.: 2-8°C
• SMILES string: COc1ncnc(NS(=O)(=O)c2ccc(N)cc2)c1OC
• InChI: 1S/C12H14N4O4S/c1-19-10-11(14-7-15-12(10)20-2)16-21(17,18)9-5-3-8(13)4-6-9/h3-7H,13H2,1-2H3,(H,14,15,16)
• InChI key: PJSFRIWCGOHTNF-UHFFFAOYSA-N

Description

General description

Chemical structure: sulfonamide

Sulfadoxin belongs to the long acting group of sulfonamides, which acts by inhibiting dihydropteroate synthase in intracellular sporozoa such as Eimeria and Toxoplasma and Plasmodium.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Sulfadoxin may be used as a reference standard for the determination of the analyte in plasma samples using packed-column supercritical fluid chromatography (SFC).

Recommended products

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Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• pictograms: GHS07,GHS09
• signalword: Warning
• hcodes: H317,H411
• pcodes: P261 - P272 - P273 - P280 - P302 + P352 - P333 + P313
• Hazard Classifications: Aquatic Chronic 2 - Skin Sens. 1
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 2
• ppe: dust mask type N95 (US), Eyeshields, Gloves