Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

View All Documentation

22128

Sigma-Aldrich

Cefotaxime sodium salt

≥98.0% (TLC)

Synonym(s):

Cefotaxim sodium salt

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C16H16N5NaO7S2
CAS Number:
64485-93-4
Molecular Weight:
477.45
Beilstein/REAXYS Number:
5711411
EC Number:
264-915-9
MDL number:
MFCD00079073
UNSPSC Code:
51101500

assay

≥98.0% (TLC)

impurities

≤5% water

solubility

H2O: 50 mg/mL, clear, light yellow

mode of action

cell wall synthesis | interferes

storage temp.

2-8°C

SMILES string

[Na+].[H][C@]12SCC(COC(C)=O)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\c3csc(N)n3)C([O-])=O

InChI

1S/C16H17N5O7S2.Na/c1-6(22)28-3-7-4-29-14-10(13(24)21(14)11(7)15(25)26)19-12(23)9(20-27-2)8-5-30-16(17)18-8;/h5,10,14H,3-4H2,1-2H3,(H2,17,18)(H,19,23)(H,25,26);/q;+1/p-1/b20-9-;/t10-,14-;/m1./s1

InChI key

AZZMGZXNTDTSME-JUZDKLSSSA-M

Looking for similar products? Visit Product Comparison Guide

General description

Chemical structure: ß-lactam

Biochem/physiol Actions

Cefotaxim inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls. As a result, bacteria lyse due to cell wall autolytic enzymes.

Other Notes

Broad spectrum third generation cephalosporin antibiotic.
This product has been replaced by C7912-SIGMA | Cefotaxime sodium salt potency: 916-964 μg per mg

Replaced by

Product No.
Description
Pricing

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
315984/1
1285841
456534/1
427805/1
404241/1

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Laetitia Betelli et al.
Talanta, 184, 210-218 (2018-04-21)
The accurate identification of β-lactamases produced by Enterobacteriaceae is a major challenge in clinical laboratories in order to optimize antimicrobial treatment and patient care. We describe here a rapid voltammetric-based method to detect and to discriminate β-lactamase activity in Enterobacteriaceae
Carola E H Rosenkilde et al.
Nature communications, 10(1), 618-618 (2019-02-08)
Antibiotic resistance is a major challenge to global public health. Discovery of new antibiotics is slow and to ensure proper treatment of bacterial infections new strategies are needed. One way to curb the development of antibiotic resistance is to design

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service