177539
Syringaldazine
98%, powder or crystals
Synonym(s):
4-Hydroxy-3,5-dimethoxybenzaldehyde azine
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product name
Syringaldazine, 98%
Quality Level
assay
98%
form
powder or crystals
mp
209-210 °C (lit.)
solubility
DMF: 5%, clear to hazy
storage temp.
2-8°C
SMILES string
COc1cc(\C=N\N=C\c2cc(OC)c(O)c(OC)c2)cc(OC)c1O
InChI
1S/C18H20N2O6/c1-23-13-5-11(6-14(24-2)17(13)21)9-19-20-10-12-7-15(25-3)18(22)16(8-12)26-4/h5-10,21-22H,1-4H3/b19-9+,20-10+
InChI key
YARKTHNUMGKMGS-LQGKIZFRSA-N
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Application
Syringaldazine has been used as a substrate to measure the enzymatic activity of recombinant laccase.
Biochem/physiol Actions
Syringaldazine (4-Hydroxy-3, 5-dimethoxybenzaldehyde azine) is a nonautooxidizable laccase-specific compound. It acts as a substrate for laccase and peroxidase in the presence of hydrogen peroxide (H2O2). Syringaldazine also acts as an electron donor in the prostaglandin H synthase (PGHS) reaction.
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Science (New York, N.Y.), 260(5108), 672-674 (1993-04-30)
Peroxidase has been thought to be the only enzyme that oxidizes monolignol precursors to initiate lignin formation in plants. A laccase was purified from cell walls of differentiating xylem of loblolly pine and shown to coincide in time and place
Applied biochemistry and biotechnology, 61(1-2), 205-209 (1996-10-01)
The prostaglandin H synthase (PGHS) reaction has been studied with syringaldazine as the electron donor. Kinetic parameters of the reaction agreed with those for commonly used electron donors. The sensitivity of the PGHS activity detection in the presence of syringaldazine
Use of syringaldazine for detection of laccase in sporophores of wood rotting fungi.
Mycologia, 66(3), 469-476 (1974-05-01)
The Journal of urology, 149(6), 1405-1408 (1993-06-01)
The value of orange juice consumption in kidney stone prevention was examined in 8 healthy men and 3 men with documented hypocitraturic nephrolithiasis. They underwent 3 phases of a metabolic study, a placebo phase and 2 treatment phases in which
Journal of nematology, 23(2), 254-258 (1991-04-01)
Isoperoxidases were detected in resistant Rossol and susceptible Roma VF tomato roots uninfected and infected by Meloidogyne incognita. Syringaldazine, guaiacol, p-phenylenediamine-pyrocatechol (PPD-PC), and indoleacetic acid (IAA) were used as substrates, and the corresponding peroxidative activities were detected either in cytoplasmic
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