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09415

Sigma-Aldrich

Sodium 4-aminosalicylate dihydrate

≥97.0% (T)

Synonym(s):

4-Amino-2-hydroxybenzoic acid sodium salt, 4-Amino-salicylic acid sodium salt

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About This Item

Empirical Formula (Hill Notation):
C7H6NNaO3 · 2H2O
CAS Number:
6018-19-5
Molecular Weight:
211.15
EC Number:
205-091-2
MDL number:
MFCD00151044
UNSPSC Code:
41116107
PubChem Substance ID:
329748763
NACRES:
NA.22

Quality Level

200

assay

≥97.0% (T)

form

powder

reaction suitability

reaction type: solution phase peptide synthesis

technique(s)

ligand binding assay: suitable

color

white to faintly beige

application(s)

peptide synthesis

SMILES string

O.O.[Na+].Nc1ccc(c(O)c1)C([O-])=O

InChI

1S/C7H7NO3.Na.2H2O/c8-4-1-2-5(7(10)11)6(9)3-4;;;/h1-3,9H,8H2,(H,10,11);;2*1H2/q;+1;;/p-1

InChI key

GMUQJDAYXZXBOT-UHFFFAOYSA-M

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Related Categories

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0001257115
1257115
1140896
1257115V
453791/1

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Shadeed Gad et al.
The Journal of pharmacy and pharmacology, 64(9), 1264-1274 (2012-08-14)
The objective of this work was to spray dry p-aminosalicylic acid (PAS) and its ammonium salt and to investigate the impact of the pore-forming agent, ammonium carbonate (AC), on the morphological, aerodynamic and physicochemical properties of the resulting powders. Microparticles
[A chronic moderate manganism poisoning treated with sodium p-aminosalicylic acid].
Wei-Ping Qin et al.
Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 29(8), 619-620 (2012-02-18)
S M Vesenbeckh et al.
Infection, 40(2), 199-202 (2011-08-13)
para-Aminosalicylic acid (PAS) is commonly used in the treatment of drug-resistant tuberculosis, including multidrug-resistant tuberculosis. Since its first use in the 1940s, hypersensitivity reactions frequently limit its use in clinical practice. Cases of successful desensitization against PAS using orally administered
V E Sagynbaeva et al.
Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, (3)(3), 40-46 (2012-07-27)
Detection of IgM and IgG Chlamydia and Mycoplasma pneumoniae indicates an aggravation of intracellular infections, including, possibly, due to immunosuppressive therapy. It is possible that the intracellular infection may mediate the occurrence of certain extraintestinal manifestations of inflammatory bowel disease
Shuichi Yano et al.
BMJ case reports, 2012, doi:10-doi:10 (2012-05-19)
Isoniazid (H) or rifampicin (R) mono-resistant disease can be treated easily and effectively with first-line drugs, while combined H and R resistance (ie, multidrug-resistant tuberculosis (MDRTB)) requires treatment with at least four agents, including a quinolone and an injectable agent.
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