07297

Xylometazoline hydrochloride

analytical standard

• Synonym(s): 2-(4-tert-Butyl-2,6-dimethylbenzyl)-2-imidazoline hydrochloride
• Empirical Formula (Hill Notation): C₁₆H₂₄N₂ · HCl
• CAS Number: 1218-35-5
• Molecular Weight: 280.84
• EC Number: 214-936-4
• MDL number: MFCD00238707
• UNSPSC Code: 41116107
• PubChem Substance ID: 329748399
• NACRES: NA.24

Properties

• grade: analytical standard
• Quality Level: 100
• assay: ≥98.0% (HPLC)
• shelf life: limited shelf life, expiry date on the label
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• impurities: ≤1.0% water
• application(s): forensics and toxicology; veterinary
• format: neat
• SMILES string: CC1=CC(C(C)(C)C)=CC(C)=C1CC2=NCCN2.Cl
• InChI: 1S/C16H24N2.ClH/c1-11-8-13(16(3,4)5)9-12(2)14(11)10-15-17-6-7-18-15;/h8-9H,6-7,10H2,1-5H3,(H,17,18);1H
• InChI key: YGWFCQYETHJKNX-UHFFFAOYSA-N

Description

General description

Xylometazoline hydrochloride is a derivative of imidazole, and a representative of the class of α1 agonists. It is commonly used in nasal decongestants, which works on the principle of constricting the blood vessels in the mucous membranes.

Application

Xylometazoline hydrochloride may be used as a reference standard in determining the xylometazoline hydrochloride content in samples of nasal drops using high performance liquid chromatography (HPLC).

Biochem/physiol Actions

α-adrenoceptor agonist; imidazoline binding site ligand.

Safety Information

• pictograms: GHS06
• signalword: Danger
• hcodes: H301
• pcodes: P301 + P310
• Hazard Classifications: Acute Tox. 3 Oral
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable