BP-Series: Biotinylated Polymeric Probes This series of glycoconjugate probes includes HOCH2CH2NH3+-salts for acidic sugars. The affinity of these probes is 102 to 105 times higher than that of the corresponding free sugars. The spacer-arm is normally –(CH2)3–, while the spacer arm for biotin is –(CH2)6–. The flexible polymer chain behaves as an additional spacer.
Used as a high molecular weight carrier, poly[N-(2-hydroxyethyl)acrylamide], abbreviated as PAA, has low non-specific sorption, and is stable to chemical and proteolytic action.
Application
Glycoconjugates are used to study the functions of carbohydrates, carbohydrate-binding proteins in biological processes, and on the discovery of new carbohydrate-mediated interactions.
Preparation Note
Purity: synthetic ω-aminoalkyl glycosides used for coupling with the polymer have a purity of >95% (HPLC and 1H-NMR)
Storage Class
13 - Non Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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