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FCMAB112F

Sigma-Aldrich

Anti-SOX-2 Antibody, clone 6G1.2, FITC conjugate

clone 6G1.2, from mouse, FITC conjugate

Synonym(s):

SRY (sex determining region Y)-box 2, SRY-related HMG-box gene 2, sex-determining region Y-box 2, transcription factor SOX2

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

100

conjugate

FITC conjugate

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

6G1.2, monoclonal

species reactivity

human, rat, mouse

technique(s)

flow cytometry: suitable

isotype

IgG2b

NCBI accession no.

NP_003097.1

UniProt accession no.

P48431

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... SOX2(6657)
mouse ... Sox2(20674)
rat ... Sox2(499593)

Related Categories

General description

Sox-2 plays a key role in embryonic stem cell development, and has been shown to help stem cells maintain a pluripotent potential. It has also been shown to be associated with uncommitted dividing stem cell and precursor cells of the developing CNS.

Specificity

SOX-2

Application

Anti-SOX-2 Antibody, clone 6G1.2, FITC conjugate is an antibody against SOX-2 for use in FC.

Quality

Evaluated by flow cytometry on undifferentiated adult Rat hippocampal neural stem cells SCR022.
Optimal working dilutions must be determined by the end user.

Target description

~34 kDa

Physical form

Purified mouse monoclonal IgG2b conjugated to FITC in PBS with less than 0.09% sodium azide and 15 mg/mL BSA.

Analysis Note

Control
Rat Neural Stem Cells.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Breanna S Borys et al.
Biotechnology and bioengineering, 117(5), 1316-1328 (2020-01-22)
Embryonic stem cells (ESCs) have almost unlimited proliferation capacity in vitro and can retain the ability to contribute to all cell lineages, making them an ideal platform material for cell-based therapies. ESCs are traditionally cultured in static flasks on a
Thalia Jimenez et al.
American journal of cancer research, 10(10), 3487-3506 (2020-11-10)
Breast cancer remains a complex disease resulting in high mortality in women. A subset of cancer stem cell (CSC)-like cells expressing aldehyde dehydrogenase 1 (ALDH1) and SOX2/OCT4 are implicated in aggressive biology of specific subtypes of breast cancer. Targeting these

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