Ubiquitin carboxyl-terminal hydrolase 10 (USP10), also known as Ubiquitin-specific-processing protease 10, belongs to the peptidase C19 family and functions to catalyze the cleavage of ubiquitin from ubiquitin-conjugated protein substrates such as p53/TP53, SNX3 and CFTR. USP10 is widely expressed and is down-regulated in renal cell carcinomas.
Immunogen
KLH-conjugated linear peptide corresponding to human USP10.
Application
Anti-USP10 Antibody is a highly specific rabbit polyclonal antibody, that targets Ubiquitin carboxyl-terminal hydrolase 10 & has been tested in western blotting & ICC.
Immunocytochemistry Analysis: 20 µg/mL from a representative lot detected USP10 in Jurkat cells.
Research Category Signaling
Research Sub Category Developmental Signaling
Quality
Evaluated by Western Blotting in Jurkat cell lysate.
Western Blotting Analysis: 2 µg/mL of this antibody detected USP10 in 15 µg of Jurkat cell lysate.
Target description
~122 kDa observed. Uniprot describes 3 isoforms at ~~87 kDa, ~88 kDa, and ~93 kDa
Physical form
Antigen Affinity Purified
Purified rabbit polyclonal in buffer containing PBS with 0.1% sodium azide.
Storage and Stability
Stable for 1 year at 2-8°C from date of receipt.
Analysis Note
Control Jurkat cell lysate
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
10 - Combustible liquids
wgk_germany
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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