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Key Documents

ABE234

Sigma-Aldrich

Anti-Friend of PRMT1 Antibody

serum, from rabbit

Synonym(s):

Chromatin target of PRMT1 protein, Friend of PRMT1 protein, Small arginine- and glycine-rich protein, SRAG, Chromatin target of PRMT1, Friend-of Prmt1, Chtop, FOP

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100 μL
$388.00

$388.00


Estimated to ship onApril 19, 2025


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100 μL
$388.00

About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

$388.00


Estimated to ship onApril 19, 2025


Request a Bulk Order

biological source

rabbit

Quality Level

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human, rat, mouse

technique(s)

ChIP: suitable
western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... CHTOP(26097)
mouse ... CHTOP(66511)
rat ... CHTOP(361990)

Related Categories

General description

The protein called Friend of PRMT1 (FOP), or more correctly Chromatin target of PRMT1 protein, or Small arginine and glycine rich protein (SRAG) is an important partner in estrogen receptor gene activation events and plays a role in 5FMC mediated desumoylation of ZNF148 and the subsequent gene activations of its target genes. Friend of PRMT1 also interacts with other methyltransferases such as PRMT5. The protein is also a component of the dynamic TREX mRNA export complex where it assists in mRNA export. The protein is expressed in the nucleus and contained in the nucleolus of various cell types including erythroid progenitor cells.

Immunogen

Epitope: C-terminus
GST-tagged recombinant protein corresponding to the C-terminus of human Friend of PRMT1.

Application

Anti-Friend of PRMT1 Antibody is an antibody against Friend of PRMT1 for use in western blotting & ChIP.
Chromatin Immunoprecipitation Analysis: A representative lot from an independent laboratory detected Friend of PRMT1 in MCF-7 cell lysate (Van Dijk, T. B., et al. (2010). Mol Cell Biol. 30(1):260-272.).
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Chromatin Biology

Quality

Evaluated by Western Blotting in A431 cell lysate.

Western Blotting Analysis: A 1:1,000 dilution from a representative lot detected Friend of PRMT1 in 10 µg of A431 cell lysate.

Target description

~32 kDa observed

Physical form

Rabbit polyclonal serum with 0.05% sodium azide.
Unpurified

Storage and Stability

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 1


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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