Receptor-interacting serine/threonine-protein kinase 1, also known as Cell death protein RIP or Receptor-interacting protein 1 (RIP-1) or Serine/threonine-protein kinase RIP, and encoded by the gene name RIPK1 or RIP or RIP1, contains 1 death domain and 1 protein kinase domain. RIPK1 is localized to the cytoplasm and plays an important role in a variety of cellular pathways including the NF-κB pathway and programmed necrotic cell death (necroptosis).
Immunogen
Epitope: Near N-terminus
RIPK1 antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human RIPK1.
Application
Immunohistochemistry Analysis (IHC): 2.5 μg/mL from a representative lot detected RIPK1 in mouse kidney tissue.
Research Category Apoptosis & Cancer
Research Sub Category Apoptosis - Additional
This Anti-RIPK1 Antibody is validated for use in Western Blotting_x000D_ and Immunohistochemistry for the detection of RIPK1.
Quality
Evaluated by Western Blotting in rat kidney tissue lysate.
Western Blotting Analysis (WB): 1 μg/mL of this antibody detected RIPK1 in rat kidney tissue lysate.
Target description
~75 kDa observed. Uncharacterized bands may be observed in some lysate(s).
Physical form
Antigen Affinity Purified
Purified rabbit polyclonal in buffer containing PBS (pH 7.2) with 0.02% sodium azide.
Storage and Stability
Stable for 1 year at 2-8°C from date of receipt.
Other Notes
Concentration: Please refer to lot specific datasheet.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
12 - Non Combustible Liquids
wgk_germany
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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