Recognizes human Histamine Receptor 4 (HR4). The immunogen shows no significant sequence homology with other histamine receptors.
Immunogen
A 17 amino acid peptide sequence within the cytoplasmic, C-terminus of human HR4 (Oda et al. 2000; Nakamura et al. 2000).
Epitope: C-terminus
Application
Anti-Histamine Receptor 4 Antibody, C-terminus detects level of Histamine Receptor 4 & has been published & validated for use in ELISA & WB.
Research Category Inflammation & Immunology
Research Sub Category Inflammation & Autoimmune Mechanisms
Western blot: 1-10 μg/mL using ECL.
ELISA: 1:10,000-1:100,000 using 50-100 ng control peptide per well (Catalog number AG217).
Optimal working dilutions must be determined by the end user.
Physical form
Affinity purified immunoglobulin. Liquid in PBS with 0.1% BSA.
Storage and Stability
Maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
12 - Non Combustible Liquids
wgk_germany
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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American journal of physiology. Renal physiology, 325(1), F105-F120 (2023-05-25)
Histamine is involved in the regulation of immune response, vasodilation, neurotransmission, and gastric acid secretion. Although elevated histamine levels and increased expression of histamine metabolizing enzymes have been reported in renal disease, there is a gap in knowledge regarding the
Functional role of histamine receptors in the renal cortical collecting duct cells.
Sudarikova, et al.
American Journal of Physiology. Cell Physiology, 322, C775-C786 (2023)
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