8.52365

Fmoc-Ser(tBu)-OPfp

Novabiochem^®

• Synonym(s): Fmoc-Ser(tBu)-OPfp, N-α-Fmoc-O-t.-butyl-L-serine pentafluorophenyl ester
• Empirical Formula (Hill Notation): C₂₈H₂₄F₅NO₅
• CAS Number: 105751-13-1
• Molecular Weight: 549.49
• MDL number: MFCD00062213
• UNSPSC Code: 12352209
• NACRES: NA.22

Properties

• Quality Level: 200
• product line: Novabiochem^®
• assay: ≥97.0% (HPLC)
• form: powder
• reaction suitability: reaction type: Fmoc solid-phase peptide synthesis
• manufacturer/tradename: Novabiochem^®
• application(s): peptide synthesis
• functional group: hydroxyl
• storage temp.: 15-25°C
• InChI: 1S/C28H24F5NO5/c1-28(2,3)38-13-19(26(35)39-25-23(32)21(30)20(29)22(31)24(25)33)34-27(36)37-12-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,18-19H,12-13H2,1-3H3,(H,34,36)/t19-/m0/s1
• InChI key: DOUJYVMLNKRFHE-IBGZPJMESA-N

Description

General description

Pre-formed pentafluorophenyl ester for coupling of serine amino-acid residues by Fmoc SPPS. Use enables bromophenol blue monitoring of amide bond formation.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS

Analysis Note

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.0% (a/a)
Purity (TLC (0004)): <2% DCU
Assay (HPLC, area%): ≥ 97.0% (a/a)
Solubility (1 mmol in 6 ml DMF): clearly soluble

To see the solvent systems used for TLC of Novabiochem^® products please click here.

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable