8.52099

Fmoc-Lys(Dnp)-OH

Novabiochem^®

• Synonym(s): Fmoc-Lys(Dnp)-OH, N-α-Fmoc-N-ε-2,4-dinitrophenyl-L-lysine
• Empirical Formula (Hill Notation): C₂₇H₂₆N₄O₈
• CAS Number: 148083-64-1
• Molecular Weight: 534.52
• UNSPSC Code: 12352209
• NACRES: NA.22

Properties

• Quality Level: 200
• product line: Novabiochem^®
• assay: ≥97.0% (HPLC); ≥98% (TLC)
• form: powder
• reaction suitability: reaction type: Fmoc solid-phase peptide synthesis
• manufacturer/tradename: Novabiochem^®
• application(s): peptide synthesis
• functional group: Fmoc
• storage temp.: 15-25°C
• InChI: 1S/C27H26N4O8/c32-26(33)24(11-5-6-14-28-23-13-12-17(30(35)36)15-25(23)31(37)38)29-27(34)39-16-22-20-9-3-1-7-18(20)19-8-2-4-10-21(19)22/h1-4,7-10,12-13,15,22,24,28H,5-6,11,14,16H2,(H,29,34)(H,32,33)/t24-/m0/s1
• InChI key: OENCMORJQAUAAJ-DEOSSOPVSA-N

Description

General description

A modified lysine derivative for the preparation of chromogenically-labeled peptides by Fmoc SPPS.The Dnp group is the preferred quencher for use in conjunction with the Mca fluorophore, making it an extremely useful tool for the synthesis of fluorescence-quenched peptide substrates.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Chromogenic Labeling of Synthetic Peptides

Linkage

Replaces: 04-12-1239

Analysis Note

Color (visual): slight yellow to yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Optical rotation α 25/D (c=1 in DMF): -13.5 - -10.5 °
Purity (TLC(011A)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Assay (HPLC, area%): ≥ 97.0 % (a/a)

To see the solvent systems used for TLC of Novabiochem^® products please click here.

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable