8.00380

Maleic acid

for synthesis

• Synonym(s): cis-Butenedioic acid, Toxilic acid
• Linear Formula: HO₂CCH=CHCO₂H
• CAS Number: 110-16-7
• Molecular Weight: 116.07
• Beilstein/REAXYS Number: 605762
• MDL number: MFCD00063177
• UNSPSC Code: 12352106
• EC Index Number: 203-742-5
• NACRES: NA.22

Properties

• vapor pressure: <0.1 hPa ( 20 °C)
• Quality Level: 200
• assay: ≥99% (acidimetric)
• form: powder
• potency: 708 mg/kg LD₅₀, oral (Rat); 1560 mg/kg LD₅₀, skin (Rabbit)
• pH: 1.3 (20 °C, 100 g/L in H₂O)
• mp: 130-135 °C (lit.)
• solubility: 478.8 g/L
• density: 1.59 g/mL at 25 °C (lit.)
• bulk density: 750‑800 kg/m³
• storage temp.: 2-30°C
• SMILES string: OC(=O)\C=C/C(O)=O
• InChI: 1S/C4H4O4/c5-3(6)1-2-4(7)8/h1-2H,(H,5,6)(H,7,8)/b2-1-
• InChI key: VZCYOOQTPOCHFL-UPHRSURJSA-N

Description

Application

• Food industry metabolomics: Maleic acid is identified as a key metabolite in the profiling of jelly fungi, aiding in the determination of biomarkers for different flesh colors, which is vital for quality assessment in the food industry (Ye et al., 2024).
• Chromatography device innovation: Maleic acid contributes to the design and characterization of an electrochemically-modulated membrane chromatography device, enhancing the precision and functionality of separation technologies in analytical chemistry (Röcker et al., 2024).

Analysis Note

Assay (HPLC, area%): ≥ 99.0 % (a/a)
Melting range (lower value): ≥ 130 °C
Melting range (upper value): ≤ 135 °C
Assay (acidimetric): ≥ 99.0 %
Identity (IR): passes test

Safety Information

• pictograms: GHS05,GHS07
• signalword: Danger
• hcodes: H302 + H312,H314,H317,H335
• pcodes: P260 - P271 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1 - Skin Sens. 1 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 8A - Combustible corrosive hazardous materials
• wgk_germany: WGK 1