553509
Ras/Rac Transformation Blocker, SCH 51344
A cell-permeable pyrazoloquinoline compound that acts as an effective blocker of Ras-induced malignant transformation and inhibits Ras/Rac-dependent dissociation of EMS1 from the actin-myosin II complex and membrane ruffling.
Synonym(s):
Ras/Rac Transformation Blocker, SCH 51344, 6-Methoxy-4-(2-((2-hydroxyethoxyl)-ethyl)amino)-3-methyl-1H-pyrazolo[3,4-b]quinoline
About This Item
Quality Level
assay
≥98% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
protect from light
color
light yellow
solubility
DMSO: 20 mg/mL
shipped in
ambient
storage temp.
−20°C
InChI
1S/C16H20N4O3/c1-10-14-15(17-5-7-23-8-6-21)12-9-11(22-2)3-4-13(12)18-16(14)20-19-10/h3-4,9,21H,5-8H2,1-2H3,(H2,17,18,19,20)
InChI key
YWEGXZZAORIRQR-UHFFFAOYSA-N
General description
Biochem/physiol Actions
Ras/Rac
Packaging
Warning
Other Notes
He, H., et al. 1998. Mol. Cell. Biol.18, 3829.
Walsh, A.B., et al. 1997. Oncogene15, 2553.
Chandra Kumar, C., et al. 1995. Cancer Res.55, 5106.
Legal Information
Storage Class
11 - Combustible Solids
wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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