516640

Phalloidin, Amanita phalloides - CAS 17466-45-4 - Calbiochem

Toxic bicyclic heptapeptide isolated from fungi.

• Synonym(s): Phalloidin, Amanita phalloides - CAS 17466-45-4 - Calbiochem
• Empirical Formula (Hill Notation): C₃₅H₄₈N₈O₁₁S
• CAS Number: 17466-45-4
• Molecular Weight: 788.87
• MDL number: MFCD03427567
• UNSPSC Code: 12352200

Properties

• Quality Level: 100
• assay: ≥95% (HPLC)
• form: crystalline solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze
• color: white
• solubility: ethanol: 10 mg/mL; methanol: 10 mg/mL
• shipped in: ambient
• storage temp.: 2-8°C
• InChI: 1S/C35H48N8O11S/c1-15-27(47)38-22-10-20-19-7-5-6-8-21(19)41-33(20)55-13-24(34(53)43-12-18(46)9-25(43)31(51)37-15)40-32(52)26(17(3)45)42-28(48)16(2)36-30(50)23(39-29(22)49)11-35(4,54)14-44/h5-8,15-18,22-26,41,44-46,54H,9-14H2,1-4H3,(H,36,50)(H,37,51)(H,38,47)(H,39,49)(H,40,52)(H,42,48)/t15-,16-,17-,18-,22-,23-,24-,25-,26+,35+/m0/s1
• InChI key: KPKZJLCSROULON-QKGLWVMZSA-N

Description

General description

Toxic bicyclic heptapeptide isolated from fungi. Useful as a potent and specific F-actin binding agent and inhibitor of F- to G-actin conversion.

Biochem/physiol Actions

Cell permeable: no

Primary Target
F-actin binding agent

Product does not compete with ATP.

Reversible: no

Warning

Toxicity: Highly Toxic (H)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 year at -20°C.

Other Notes

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Mathews, J.B., et al. 1997. Am. J. Physiol. 272, C254.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials