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Key Documents

480352

Sigma-Aldrich

2.5S NGF, Mouse Submaxillary Glands

Synonym(s):

2.5S-Nerve Growth Factor

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About This Item

UNSPSC Code:
12352202

assay

≥95% (HPLC)

Quality Level

form

lyophilized

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

shipped in

ambient

storage temp.

2-8°C

General description

Native 2.5S nerve growth factor from mouse submaxillary glands. Enhances survival, phagocytosis, and generation of superoxide in murine neutrophils. Reported to stimulate extracellular matrix invasion by human myeloma cells.
Native 2.5S nerve growth factor from mouse submaxillary glands. Enhances the survival, phagocytosis, and generation of superoxide in murine neutrophils. Reported to stimulate extracellular matrix invasion by human myeloma cells.

Biochem/physiol Actions

ED₅₀ ≤ 15 ng/ml using a PC-12 neurite outgrowth assay

Warning

Toxicity: Standard Handling (A)

Physical form

Lyophilized from sterile-filtered PBS.

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 weeks at -20°C.
Reconstitute to ≥10 µg/ml in sterile H₂O or buffer containing 2% BSA.

Other Notes

Hermann, J.L., et al. 1993. Mol. Cell. Biol. 4, 1205.
Raffioni, S., and Bradshaw, R.A. 1992. Proc. Natl. Acad. Sci. USA89, 9121.
Traverse, S., et al. 1992. Biochem. J.288, 351.
Levi-Montalcini, R. 1987. In Vitro Cell. Dev. Biol.23, 227.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1


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