235429

Caspase Inhibitor Set I

The Caspase Inhibitor Set I controls the biological activity of Caspase-1. This collection of small molecule/inhibitor is primarily used for Cancer applications.

• UNSPSC Code: 12352200
• NACRES: NA.54

Properties

• Quality Level: 100
• form: solid
• potency: 200 pM K_i
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; desiccated
• shipped in: ambient
• storage temp.: −20°C

Description

General description

Contains 1 mg of Caspase-3 Inhibitor II, Z-DEVD-FMK (Cat. No. 264155); 1 mg of Caspase-1 Inhibitor I, Ac-YVAD-CHO (Cat. No. 400010); and 1 mg of Caspase Inhibitor I, Z-VAD-FMK (Cat. No. 627610). Supplied with a data sheet.

Biochem/physiol Actions

Cell permeable: yes

Primary Target
caspase-1

Reversible: no

Secondary Target
Caspase-3, Caspase-4, Caspase-5, Caspase-6, Caspase-7, Caspase-8, Caspase-10

Warning

Toxicity: Standard Handling (A)

Other Notes

Masuda, Y., et al. 1997. Biochem. Biophys. Res. Com.234, 641.
Slee, E.A., et al. 1996. Biochem. J.315, 21.
Zhu, H., et al. 1995. FEBS Lett.374, 303.
Walker, N.P.C., et al. 1994. Cell 78, 343.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 11 - Combustible Solids