Calmodulin is a ubiquitous Ca2+-binding protein that serves as a physiological effector of a wide range of biological processes. Purified from bovine brain.
Synonym(s):
Calmodulin, Bovine Brain, CaM, Ca 2+/Calmodulin, CaM, Ca2+/Calmodulin
A ubiquitous Ca2+-binding protein distributed in eukaryotic cells that serves as a major physiological effector for a wide range of cellular responses. The Ca2+-calmodulin complex is involved in the maintenance of intracellular Ca2+ homeostasis, as well as in the regulation of the intracellular concentration of other second messengers, such as cyclic AMP and inositol trisphosphate. Calmodulin purified from bovine brain.
Note: This product is not to be used for animal treatment, in vivo research or in any other contact procedure with livestock.
Warning
Toxicity: Standard Handling (A)
Unit Definition
One unit is defined as the amount of calmodulin that gives rise to 50% of the maximal enzyme activation of a standard level of activator-deficient 3ʹ,5ʹ-cyclic nucleotide phosphodiesterase.
Physical form
Lyophilized from 150 mM NaCl, 50 mM Tris-HCl, 2 mM EDTA, pH 7.6.
Reconstitution
Following reconstitution, aliquot and freeze (-20°C or -70°C). Stock solutions are stable for up to 2 months at -20°C or for up to 4 months at -70°C.
Other Notes
Carl, A., et al. 1990. J. Physiol.429, 205. Appleman, M.M., et al. 1985. J. Cyclic Nucleotide and Protein Phosph. Res.10, 417. Cheung, W.T. 1979. Science207, 19. Sharma, R.K., and Wang, J.H. 1979. Adv. Cyclic Nucleotide Res.10, 187. Wang, J.H., and Waisman, D.M. 1979. Curr. Topics Cell. Reg.15, 47. Watterson, A., et al. 1976. J. Biol. Chem.251, 4501.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
Certificates of Analysis (COA)
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