14-459-M
Abl Protein, active, mouse, 10 µg
Active, recombinant mouse Abl, residues 27-1123, containing N-terminal His-6 tag, for use in Kinase Assays.
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About This Item
UNSPSC Code:
12352202
eCl@ss:
32160405
NACRES:
NA.32
Recommended Products
biological source
mouse
Quality Level
100
300
recombinant
expressed in baculovirus infected Sf21 cells
mol wt
Mw 123.5 kDa
manufacturer/tradename
Upstate®
technique(s)
activity assay: suitable (kinase)
NCBI accession no.
UniProt accession no.
General description
Product Source: Expressed by baculovirus in Sf21
Recombinant mouse Abl, residues 27-1123, containing N-terminal His6 tag
Biochem/physiol Actions
Protein Target: Abl
Target Sub-Family: TK
Packaging
Also available in 250 µg size --call for pricing and availability and reference catalog number 14-459M when ordering the 250 µg size.
Quality
routinely evaluated by phosphorylation of Abltide
Physical form
Ni2+/NTA-agarose
Storage and Stability
1 year at -70°C
Other Notes
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
signalword
Warning
hcodes
Hazard Classifications
Skin Sens. 1
Storage Class
12 - Non Combustible Liquids
wgk_germany
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Activation of the c-Abl tyrosine kinase in the stress response to DNA-damaging agents.
Kharbanda, S, et al.
Nature, 376, 785-788 (1995)
B B Brasher et al.
The Journal of biological chemistry, 275(45), 35631-35637 (2000-08-31)
Using the specific Abl tyrosine kinase inhibitor STI 571, we purified unphosphorylated murine type IV c-Abl and measured the kinetic parameters of c-Abl tyrosine kinase activity in a solution with a peptide-based assay. Unphosphorylated c-Abl exhibited substantial peptide kinase activity
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