1.08510

Vanillin

EMPROVE^® ESSENTIAL, Ph. Eur., BP, NF

• Synonym(s): Vanillin, 4-Hydroxy-3-methoxybenzaldehyde
• Linear Formula: (CH₃O)(OH)C₆H₃CHO
• CAS Number: 121-33-5
• Molecular Weight: 152.15
• MDL number: MFCD00006942
• UNSPSC Code: 12352114
• EC Index Number: 204-465-2

Properties

• agency: BP; NF; Ph. Eur.
• Quality Level: 500
• vapor pressure: 0.0029 hPa ( 25 °C)
• product line: EMPROVE^® ESSENTIAL
• form: solid
• autoignition temp.: >400 °C
• technique(s): API processing | cocrystal formation: suitable
• pH: 4.3 (20 °C, 10 g/L in H₂O)
• mp: 80-83.5 °C
• transition temp: flash point 160 °C
• solubility: 9 g/L
• density: 1.06 g/cm³ at 20 °C
• application(s): liquid formulation; pharmaceutical; solid formulation
• storage temp.: 15-25°C
• InChI: 1S/C8H8O3/c1-11-8-4-6(5-9)2-3-7(8)10/h2-5,10H,1H3
• InChI key: MWOOGOJBHIARFG-UHFFFAOYSA-N

Description

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our EMPROVE^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Vanillin is a commonly used ingredient in food and pharmaceutics. In pharmaceutical applications, vanillin has been used primarily as flavor enhancer for oral dosage forms.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H319
• pcodes: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Eye Irrit. 2
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: 319.6 - 321.4 °F - closed cup
• flash_point_c: 159.8 - 160.8 °C - closed cup