1.06357

Sodium disulfite

(sodium metabisulfite), EMPROVE^® ESSENTIAL, Ph. Eur., BP, JP, NF, E 223

• Synonym(s): Sodium disulfite, Sodium metabisulfite, Sodium pyrosulfite, Disulfite, Pyrosulfite
• Empirical Formula (Hill Notation): Na₂O₅S₂
• CAS Number: 7681-57-4
• Molecular Weight: 190.11
• MDL number: MFCD00167602
• UNSPSC Code: 12352302
• E Number: E223
• EC Index Number: 231-673-0

Properties

• agency: BP; JP; NF; Ph. Eur.
• Quality Level: 500
• product line: EMPROVE^® ESSENTIAL
• form: solid
• pH: 3.5-5 (20 °C, 50 g/L in H₂O)
• mp: 150 °C (decomposition)
• density: 2.36 g/cm³ at 20 °C
• application(s): liquid formulation; ophthalmics; pharmaceutical; semi-solid formulation; solid formulation
• storage temp.: 15-25°C
• InChI: 1S/2Na.H2O5S2/c;;1-6(2)5-7(3)4/h;;(H,1,2)(H,3,4)/q2*+1;/p-2
• InChI key: LDTLADDKFLAYJA-UHFFFAOYSA-L

Description

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our EMPROVE^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Sodium disulfite has reducing and anti-septic properties with broad range of applications in pharmaceutical, cosmetic and food industry. It is commonly used as preservative and antioxidant, especially for liquid and semi-solid application. In the food industry it is can help preserving food products and maintaining their fresh appearance.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• pictograms: GHS05,GHS07
• signalword: Danger
• hcodes: H302,H318
• pcodes: P264 - P270 - P280 - P301 + P312 - P305 + P351 + P338 - P501
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1
• supp_hazards: EUH031
• Storage Class: 13 - Non Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable