1.00803

L(+)-Tartaric acid

powder, EMPROVE^® ESSENTIAL, Ph. Eur., BP, ChP, JP, NF, E 334

• Synonym(s): L(+)-Tartaric acid, 2,3-Dihydroxybutanedioic acid
• Linear Formula: HOOCCH(OH)CH(OH)COOH
• CAS Number: 87-69-4
• Molecular Weight: 150.09
• MDL number: MFCD00064207
• UNSPSC Code: 12352106
• E Number: E334
• EC Index Number: 201-766-0

Properties

• agency: BP; ChP; JP; NF; Ph. Eur.
• Quality Level: 500
• vapor pressure: <5 Pa ( 20 °C)
• product line: EMPROVE^® ESSENTIAL
• assay: 99.7-100.5% dry basis (acidimetric)
• form: powder
• autoignition temp.: 425 °C
• technique(s): API processing | cocrystal formation: suitable; API processing | salt formation: suitable
• pH: 1.6 (25 °C, 100 g/L in H₂O)
• mp: 168-170 °C
• transition temp: flash point 210 °C
• solubility: 1390 g/L
• density: 1.76 g/cm³ at 20 °C
• bulk density: 1000 kg/m³
• cation traces: As: ≤0.0001%; Ca: ≤0.0200%; Ca:, passes test; Hg: ≤0.0001%; Pb: ≤0.0002%; heavy metals (as Pb): ≤0.0010%
• application(s): liquid formulation; pharmaceutical; semi-solid formulation; solid formulation
• storage temp.: 2-30°C
• InChI: 1S/C4H6O6/c5-1(3(7)8)2(6)4(9)10/h1-2,5-6H,(H,7,8)(H,9,10)
• InChI key: FEWJPZIEWOKRBE-UHFFFAOYSA-N

Description

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our EMPROVE^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Tartaric acid is a commonly used ingredient in both food and pharmaceutics. In pharmaceutical applications, tartaric acid has been used primarily as a pH modifier, and in the production of effervescent formulations.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• pictograms: GHS05
• signalword: Danger
• hcodes: H318
• pcodes: P280 - P305 + P351 + P338
• Hazard Classifications: Eye Dam. 1
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: 302.0 °F - closed cup
• flash_point_c: 150 °C - closed cup