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Key Documents

05-954

Sigma-Aldrich

Anti-TCL1 Antibody

culture supernatant, Upstate®

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

antibody form

culture supernatant

antibody product type

primary antibodies

clone

monoclonal

species reactivity

human

manufacturer/tradename

Upstate®

technique(s)

immunohistochemistry: suitable
western blot: suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... TCL1A(8115)

Specificity

TCL1A, no cross-reactivity with TML1 (TCL1B) or MTCP1

Immunogen

KLH-conjugated, synthetic peptide corresponding to amino acids 60-73 (RPMTPTQIGPSLLP) of human TCL1A

Application

Research Category
Inflammation & Immunology
Research Sub Category
Immunoglobulins & Immunology
This Anti-TCL1 Antibody is validated for use in WB, IH for the detection of TCL1.

Quality

Routinely evaluated by immunoblot in RIPA lysates from Raji cells

Target description

14 kD

Physical form

Cell culture supernatant

Storage and Stability

2 years at -20°C from date of shipment

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 1


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Crystal structures of Tcl1 family oncoproteins and their conserved surface features.
Petock, John M, et al.
TheScientificWorldJournal, 2, 1876-1884 (2002)
Structural basis for the co-activation of protein kinase B by T-cell leukemia-1 (TCL1) family proto-oncoproteins.
Auguin, Daniel, et al.
The Journal of Biological Chemistry, 279, 35890-35902 (2004)
TCL1: a new drug target in lymphoid and germ-cell malignancies?
Lock, Richard B
The International Journal of Biochemistry & Cell Biology, 35, 1614-1618 (2003)
TCL1 is a diagnostic marker for intratubular germ cell neoplasia and classic seminoma.
Dengfeng Cao,Zhaoli Lane,Robert William Allan,Peng Wang,Charles Chuanhai Guo,Yan Peng,Jianping Li
Histopathology null
A systematic approach to diagnosis of mature T-cell leukemias reveals heterogeneity among WHO categories
Herling, M. et al.
Blood, 104, 328-335 (2004)

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