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V-033

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Tocopheryl acetate (Vitamin E acetate) solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Empirical Formula (Hill Notation):
C31H52O3
CAS Number:
52225-20-4
Molecular Weight:
472.74
EC Number:
200-835-2
UNSPSC Code:
41116107
NACRES:
NA.24

grade

certified reference material

Quality Level

300

form

liquid

feature

(Snap-N-Spike®)

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

clinical testing
clinical testing

format

single component solution

storage temp.

−20°C

InChI

1S/C31H52O3/c1-21(2)13-10-14-22(3)15-11-16-23(4)17-12-19-31(9)20-18-28-26(7)29(33-27(8)32)24(5)25(6)30(28)34-31/h21-23H,10-20H2,1-9H3/t22-,23-,31-/m1/s1

InChI key

ZAKOWWREFLAJOT-CEFNRUSXSA-N

General description

Tocopheryl acetate is a natural form of Vitamin E, used as a fortifying agent and dietary supplement for Vitamin E in food. It is also the main ingredient of skin care products and dermatological preparations. Tocopheryl acetate in combination with α-tocopherol has been used in the therapy of conditions such as sterility, muscular dystrophy, cardiac vascular disorders and anemia.

Application

This internal standard is suitable for HPLC or LC-MS/MS Vitamin E testing applications such as quality control testing of Vitamin E fortified foods, dietary supplements, or pharmaceuticals.
Tocopheryl Acetate (Vitamin E acetate) may be used as an analytical standard for the determination of the analyte in aquatic organisms, fish feed and pharmaceutical formulations by colorimetric and chromatography techniques, respectively.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

related product

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V-021

(+)-γ−Tocopherol (Vitamin E) solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

V-041

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V-060

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V-042

Vitamin K2 (MK-4)-13C6 solution, 10 μg/mL in acetonitrile, certified reference material, ampule of 1 mL, Cerilliant®

V-046

(±)-gamma-Tocopherol-D3 solution, 500 μg/mL in methanol, certified reference material, ampule of 1 mL

V-090

Ubiquinol solution, 1 mg/mL (0.1% BHT (w/v) and 0.1% TFA (v/v) in Ethanol), certified reference material, ampule of 1 mL, Cerilliant®

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes,Central nervous system

Storage Class

3 - Flammable liquids

wgk_germany

WGK 2

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Simultaneous determination of alpha-tocopheryl acetate and tocopherols in aquatic organisms and fish feed
Huo JZ, et al
Journal of Chromatography. B, Biomedical Sciences and Applications, 724(2), 249-255 (1999)
Calorimetric and infrared spectroscopic studies of the interaction of a-tocopherol and a-tocopheryl acetate with phospholipid vesicles
Villalain J, et al.
European Journal of Biochemistry, 158(1), 141-147 (1986)
A S Amin
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 51(3), 267-272 (2001-05-10)
A simple, accurate and sensitive method for the determination of micro amounts of vitamin E (V(E)) in pure form and in multi-vitamin capsules is described. The method is based on the reduction of tetrazolium blue in slightly alkaline medium by

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