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M-919

Supelco

Mianserin hydrochloride solution

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Empirical Formula (Hill Notation):
C18H21ClN2
CAS Number:
21535-47-7
Molecular Weight:
300.83
EC Number:
200-659-6
UNSPSC Code:
41116107
NACRES:
NA.24

grade

certified reference material

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

1.0 mg/mL in methanol (as free base)

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

storage temp.

−20°C

SMILES string

Cl.CN1CCN2C(C1)c3ccccc3Cc4ccccc24

InChI

1S/C18H20N2.ClH/c1-19-10-11-20-17-9-5-3-7-15(17)12-14-6-2-4-8-16(14)18(20)13-19;/h2-9,18H,10-13H2,1H3;1H

InChI key

YNPFMWCWRVTGKJ-UHFFFAOYSA-N

General description

Mianserin is a tetracyclic antidepressant prescribed for the treatment of depression and is sold under the trade names Lumin and Tolvon. This certified solution standard is applicable for use in LC/MS or GC/MS applications for urine drug testing, clinical toxicology, and forensic analysis. This tetracyclic antidepressant functions as a noradrenergic and a specific serotonergic antidepressant with anxiolytic, hypnotic, antiemetic, orexigenic, and antihistamine effects.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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Description
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Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes

Storage Class

3 - Flammable liquids

wgk_germany

WGK 1

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Marij Zuidersma et al.
Journal of psychosomatic research, 74(1), 25-30 (2013-01-01)
Evaluating the effects of implementing an antidepressant treatment strategy in depressed myocardial infarction (MI)-patients on long-term cardiovascular outcomes and all-cause mortality. MI-patients were evaluated for the presence of a diagnosis of post-MI depression at 3, 6, 9 and 12months after
Clinical practice. Chronic pruritus.
Gil Yosipovitch et al.
The New England journal of medicine, 368(17), 1625-1634 (2013-04-26)
I Berling et al.
Clinical toxicology (Philadelphia, Pa.), 52(1), 20-24 (2013-11-16)
There is limited information on mirtazapine overdose, but cases of severe effects (seizures, serotonin toxicity and coma) have been reported. We aimed to investigate the clinical effects and complications of mirtazapine overdose. This was an observational case series of mirtazapine
Eveline Jaquenoud Sirot et al.
Journal of clinical psychopharmacology, 32(5), 622-629 (2012-08-29)
Pharmacogenetic tests and therapeutic drug monitoring may considerably improve the pharmacotherapy of depression. The aim of this study was to evaluate the relationship between the efficacy of mirtazapine (MIR) and the steady-state plasma concentrations of its enantiomers and metabolites in
Seda G Sagdinc et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 104, 222-234 (2012-12-26)
Mirtazapine (±)-1,2,3,4,10,14b-hexahydro-2-methylpyrazino(2,1-a)pyrido(2,3-c)(2)benzazepine is a compound with antidepressant therapeutic effects. It is the 6-aza derivative of the tetracyclic antidepressant mianserin (±)-2-methyl-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine. The FT-IR and FT-Raman spectra of mirtazapine have been recorded in 4000-400 cm(-1) and 3500-10 cm(-1), respectively. The optimized geometry
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