G-017

Gabapentin-D₁₀ solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• Empirical Formula (Hill Notation): C₉D₁₀H₇NO₂
• CAS Number: 1126623-20-8
• Molecular Weight: 181.30
• EC Number: 200-659-6
• MDL number: MFCD16294730
• UNSPSC Code: 41116107
• PubChem Substance ID: 329799800
• NACRES: NA.24

Properties

• grade: certified reference material
• Quality Level: 300
• form: liquid
• feature: Snap-N-Spike^®/Snap-N-Shoot^®
• packaging: ampule of 1 mL
• manufacturer/tradename: Cerilliant^®
• concentration: 1.0 mg/mL in methanol
• technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• application(s): clinical testing
• format: single component solution
• storage temp.: −20°C
• SMILES string: [2H]C1([2H])C([2H])([2H])C([2H])([2H])C(CN)(CC(O)=O)C([2H])([2H])C1([2H])[2H]
• InChI: 1S/C9H17NO2/c10-7-9(6-8(11)12)4-2-1-3-5-9/h1-7,10H2,(H,11,12)/i1D2,2D2,3D2,4D2,5D2
• InChI key: UGJMXCAKCUNAIE-YXALHFAPSA-N

Description

General description

Sold under the trade names Neurontin^®, Nupentin, or Gabarone, gabapentin is an anticonvulsant drug used primarily for treatment of seizures, fibromyalgia, and chronic neuropathic pain. This internal standard is suitable for GC/MS or LC/MS testing or isotope dilution methods of gabapentin in forensic analysis, clinical toxicology, pain prescription monitoring, or urine drug testing.

Application

• Quantitative analysis in serum: Gabapentin-D₁₀ serves as a reliable internal standard in the development and validation of rapid liquid chromatography/tandem mass spectrometry methods. This application facilitates the accurate quantitation of gabapentin alongside buprenorphine in human serum, critical for clinical pharmacology and therapeutic monitoring (Phillips et al., 2021).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Neurontin is a registered trademark of Warner-Lambert Co.

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• pictograms: GHS02,GHS06,GHS08
• signalword: Danger
• hcodes: H225,H301 + H311 + H331,H370
• pcodes: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• target_organs: Eyes
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 1
• flash_point_f: 49.5 °F - closed cup
• flash_point_c: 9.7 °C - closed cup