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F-918

Supelco

Fluoxetine hydrochloride solution

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Empirical Formula (Hill Notation):
C17H19ClF3NO
CAS Number:
56296-78-7
Molecular Weight:
345.79
MDL number:
MFCD00214288
UNSPSC Code:
41116107
NACRES:
NA.24

grade

certified reference material

Quality Level

300

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

1.0 mg/mL in methanol (as free base)

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

storage temp.

2-8°C

SMILES string

Cl.CNCCC(Oc1ccc(cc1)C(F)(F)F)c2ccccc2

InChI

1S/C17H18F3NO.ClH/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20;/h2-10,16,21H,11-12H2,1H3;1H

InChI key

GIYXAJPCNFJEHY-UHFFFAOYSA-N

Gene Information

human ... SLC6A4(6532)

Related Categories

General description

A Snap-N-Spike® reference solution applicable for use in clinical toxicology, urine drug testing, or forensic analysis by LC-MS/MS or GC/MS. Fluoxetine is a pharmaceutical antidepressant which functions as a selective serotonin reuptake inhibitor (SSRI). Fluoxetine is sold under the trade name Prozac® for treatment of psychological conditions including major depression and obsessive-compulsive disorder.

Application


  • Fluoxetine HCl in Neuropharmacology: The development of dispersive liquid-liquid microextraction techniques for trace analysis of fluoxetine showcases its crucial role in neuropharmacological research, enabling precise quantification and study of its effects on neurotransmitter systems (Azadkish et al., 2023).

  • Research Grade Fluoxetine for Biochemical Studies: A novel system for bioelectronic delivery of treatments, including fluoxetine, directed toward enhancing wound healing processes, highlights the application of fluoxetine hydrochloride solution in biomedical engineering and tissue regeneration research (Baniya et al., 2023).

  • Fluoxetine Hydrochloride for Antidepressant Assays: Studies on antidepressant and anxiolytic effects of fermented food products indirectly utilize fluoxetine as a comparative standard, aiding in the development of functional foods with potential mental health benefits (Santiago-López et al., 2022).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Prozac is a registered trademark of Eli Lilly and Co.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes

Storage Class

3 - Flammable liquids

wgk_germany

WGK 2

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Animal behavior case of the month. Underlying anxiety disorder in an aggressive dog.
Cam Day et al.
Journal of the American Veterinary Medical Association, 242(8), 1071-1073 (2013-04-04)
Carole Di Poi et al.
Aquatic toxicology (Amsterdam, Netherlands), 132-133, 84-91 (2013-03-12)
Recent ecotoxicological studies highlight the increasing presence of pharmaceuticals discharged in the aquatic environment. Amongst them is the antidepressant fluoxetine (FLX), a selective serotonin reuptake inhibitor, primarily indicated for treatment of depression. The effect of chronic exposure to FLX on
S Ceccatelli et al.
Journal of internal medicine, 273(5), 490-497 (2013-04-23)
Amongst environmental chemical contaminants, methylmercury (MeHg) remains a major concern because of its detrimental effects on developing organisms, which appear to be particularly susceptible to its toxicity. Here, we investigated the effects of low MeHg levels on the development of
B Nardi et al.
European review for medical and pharmacological sciences, 17(11), 1546-1551 (2013-06-19)
Major depressive disorder (MDD) is a common disorder during adolescence and it is associated with an increased risk of suicide, poor school performance, impaired social skills, social withdrawal and substance abuse. Further, as many depressive episode in adolescents do not
Susanne E Ahmari et al.
Science (New York, N.Y.), 340(6137), 1234-1239 (2013-06-08)
Although cortico-striato-thalamo-cortical (CSTC) circuit dysregulation is correlated with obsessive compulsive disorder (OCD), causation cannot be tested in humans. We used optogenetics in mice to simulate CSTC hyperactivation observed in OCD patients. Whereas acute orbitofrontal cortex (OFC)-ventromedial striatum (VMS) stimulation did
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