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LM6004

Avanti

d5-DG ISTD Mix II

Avanti Research™ - A Croda Brand LM6004

Synonym(s):

d5-DG ISTD Mix II, d5-Diglyceride Mixture Internal Standard, toluene:methanol (1:1)

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About This Item

UNSPSC Code:
41116107
NACRES:
NA.25

form

solution

packaging

pkg of 1 × 1 mL (LM6004-1EA)

manufacturer/tradename

Avanti Research™ - A Croda Brand LM6004

concentration

~10 μg/mL (Refer to C of A for lot specific concentration. )

application(s)

lipidomics
metabolomics

shipped in

dry ice

storage temp.

−20°C

General description

Deuterated diglyceride (DG) Mixture II contains: 1,3-16:1 D5 DG 1,3-18:0 D5 DG 1,3-18:1 D5 DG 1,3-18:2 D5 DG.

Application

d5-DG ISTD Mix II or d5-Diglyceride Mixture Internal Standard has been used as an internal standard mixture for diacylglycerol analysis by high-performance liquid chromatography/tandem mass spectrometry (LC/MS2). It has also been used as an internal standard mixture in lipid extraction from 3-hydroxy-isobutyrate (3-HIB)-fed mouse muscle samples and in liquid chromatography-mass spectrometry (LC-MS) lipidomics.

Packaging

2 mL Amber Glass Sealed Ampule (LM6004-1EA)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

also commonly purchased with this product

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Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 3 - Asp. Tox. 1 - Flam. Liq. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 2 - STOT SE 1 - STOT SE 3

target_organs

Central nervous system, Eyes

Storage Class

3 - Flammable liquids

wgk_germany

WGK 3

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Diminished anabolic signaling response to insulin induced by intramuscular lipid accumulation is associated with inflammation in aging but not obesity
Rivas DA, et al.
American Journal of Physiology. Regulatory, Integrative and Comparative Physiology, 310(7), R561-R569 (2016)
R C Fitzgerald et al.
The Journal of clinical investigation, 98(9), 2120-2128 (1996-11-01)
Barrett's esophagus (BE), or specialized intestinal metaplasia, is a premalignant heterogeneous epithelium associated with reflux and an increased risk for adenocarcinoma. Since acid is a major component of refluxate, we investigated its effects ex vivo on cell differentiation as determined
Cholsoon Jang et al.
Nature medicine, 22(4), 421-426 (2016-03-08)
Epidemiological and experimental data implicate branched-chain amino acids (BCAAs) in the development of insulin resistance, but the mechanisms that underlie this link remain unclear. Insulin resistance in skeletal muscle stems from the excess accumulation of lipid species, a process that
Donato A Rivas et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 310(7), R561-R569 (2016-01-15)
The loss of skeletal muscle mass is observed in many pathophysiological conditions, including aging and obesity. The loss of muscle mass and function with aging is defined as sarcopenia and is characterized by a mismatch between skeletal muscle protein synthesis

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