890860C

14:0 TAP

Avanti Research^™ - A Croda Brand 890860C

• Synonym(s): 1,2-dimyristoyl-3-trimethylammonium-propane (chloride salt)
• Empirical Formula (Hill Notation): C₃₄H₆₈NO₄Cl
• CAS Number: 197974-74-6
• Molecular Weight: 590.36
• UNSPSC Code: 12352211
• NACRES: NA.25

Properties

• form: liquid
• packaging: pkg of 1 × 2.5 mL (890860C-25mg); pkg of 2 × 4 mL (890860C-200mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 890860C
• concentration: 10 mg/mL (890860C-25mg); 25 mg/mL (890860C-200mg)
• lipid type: cationic lipids; transfection
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: [H]C(C[N+](C)(C)C)(OC(CCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCC)=O.[Cl-]

Description

General description

1,2-dimyristoyl-3-trimethylammonium-propane (14:0 TAP) is a saturated cationic lipid with a positively charged headgroup. It has an alkyl chain length with 14 carbon atoms.

Application

1,2-dimyristoyl-3-trimethylammonium-propane (14:0 TAP) is suitable for:

• preparation of cationic liposomes
• reconstitution of bacteriorhodopsin (BR) and proteorhodopsin (PR) into liposomes
• composing lipid–styrene maleic acid (SMA) complexes
• liposome preparation by double emulsion method

Biochem/physiol Actions

1,2-dimyristoyl-3-trimethylammonium-propane (14:0 TAP) is useful for bicelle formation. Bicelles can be integrated into standard crystallization protocols, and in contrast to micelles, bicelles maintain the protein in a more native bilayer environment allowing proteins to be captured in a more biologically relevant orientation.

Packaging

5 mL Clear Glass Sealed Ampule (890860C-200mg)

5 mL Clear Glass Sealed Ampule (890860C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• pictograms: GHS06,GHS08
• signalword: Danger
• hcodes: H302,H315,H319,H331,H336,H351,H361d,H372
• pcodes: P202 - P301 + P312 - P302 + P352 - P304 + P340 + P311 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
• target_organs: Liver,Kidney, Respiratory system
• Storage Class: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• wgk_germany: WGK 3
• flash_point_f: does not flash
• flash_point_c: does not flash