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878115C

Avanti

C16-04:0 PC

Avanti Research™ - A Croda Brand 878115C

Synonym(s):

1-O-hexadecyl-2-butyryl-sn-glycero-3-phosphocholine

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About This Item

Empirical Formula (Hill Notation):
C28H58NO7P
CAS Number:
85405-03-4
Molecular Weight:
551.74
UNSPSC Code:
12352211
NACRES:
NA.25

form

liquid

packaging

pkg of 1 × 1 mL (878115C-5mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 878115C

concentration

5 mg/mL (878115C-5mg)

shipped in

dry ice

storage temp.

−20°C

SMILES string

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCC)=O)COCCCCCCCCCCCCCCCC)=O

General description

C16-04:0 PC, also known as 1-O-hexadecyl-2-butyryl-sn-glycero-3-phosphocholine (butanoyl-PAF), is a platelet-activating factor (PAF) analog. It is synthesized non-enzymatically in the oxidized-low density lipoprotein (Ox-LDL) particles. Butanoyl-PAF is mainly produced in the body during high oxidative stress. This lipid mediator exhibits pro-inflammatory activity.[1]

application

C16-04:0 PC or 1-O-hexadecyl-2-butyryl-sn-glycero-3-phosphocholine may be used to study its physicochemical properties and its interaction with peptides derived from the C-terminal domains of human apolipoprotein E.[1]

Packaging

5 mL Clear Glass Sealed Ampule (878115C-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk_germany

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash

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Sunil A Nankar et al.
Biochimie, 95(6), 1196-1207 (2013-02-05)
Apolipoprotein-derived peptides are promising candidates for the treatment of various inflammatory conditions and the main mechanism proposed for the protective action of these peptides includes binding to pro-inflammatory lipid mediators with high affinity and facilitating their sequestration/metabolism/clearance in the body.

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