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860648P

Avanti

C20 Ceramide (d17:1/20:0)

Avanti Research™ - A Croda Brand 860648P, powder

Synonym(s):

N-arachidoyl-D-erythro-sphingosine (C17 base)

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About This Item

Empirical Formula (Hill Notation):
C37H73NO3
CAS Number:
474944-00-8
Molecular Weight:
579.98
UNSPSC Code:
12352100
NACRES:
NA.25

form

powder

packaging

pkg of 1 × 10 mg (860648P-10mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 860648P

lipid type

deuterated lipids
sphingolipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

OC[C@]([H])(NC(CCCCCCCCCCCCCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCC

General description

C20 Ceramide (d17:1/20:0) is a synthetic ceramide containing C17 analog of sphingosine with arachidonic acid. Ceramide synthase 2 catalyzes the synthesis of C20 Ceramide. Ceramide is the key component of sphingolipids.

Application

C20 Ceramide (d17:1/20:0) has been used as an internal standard to measure the sphingolipid content in liver by ultra-high performance liquid chromatography tandem mass spectrometry (UHPLC/MS/MS).

Biochem/physiol Actions

Ceramides play an important role in cell signaling, cell differentiation, proliferation and apoptosis.

Packaging

5 mL Amber Glass Screw Cap Vial (860648P-10mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

No data available

flash_point_c

No data available

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Ceramide Structure and Derivatives
Kumari A
Sweet Biochemistry: Remembering Structures, Cycles, and Pathways by Mnemonics (2018)
Hady Razak Hady et al.
Journal of clinical medicine, 8(12) (2019-12-18)
The liver plays a central role in the glucose and lipid metabolism. Studies performed on animal models have shown an important role of lipid accumulation in the induction of insulin resistance. We sought to explain whether in obese humans, the
Luisa Coderch et al.
American journal of clinical dermatology, 4(2), 107-129 (2003-01-30)
Ceramides are the major lipid constituent of lamellar sheets present in the intercellular spaces of the stratum corneum. These lamellar sheets are thought to provide the barrier property of the epidermis. It is generally accepted that the intercellular lipid domain
Ling Chen et al.
Oncology reports, 34(1), 447-454 (2015-05-16)
Endocannabinoids and ceramides have demonstrated growth inhibition, cell death induction and pro-apoptotic activity in cancer research. In the present study, we describe the profiles of two major endocannabinoids, ceramides, free fatty acids and relevant metabolic enzymes in 47 pairs of

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