840065C

18:0-22:6 PS

1-stearoyl-2-docosahexaenoyl-sn-glycero-3-phospho-L-serine (sodium salt), chloroform

• Synonym(s): 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phospho-L-serine (sodium salt); PS(18:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)); 110675
• Empirical Formula (Hill Notation): C₄₆H₇₇NO₁₀PNa
• CAS Number: 474943-18-5
• Molecular Weight: 858.07
• UNSPSC Code: 12352211
• NACRES: NA.25

Properties

• assay: >99% (TLC)
• form: liquid
• packaging: pkg of 1 × 2.5 mL (840065C-25mg); pkg of 1 × 4 mL (840065C-100mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 840065C
• concentration: 10 mg/mL (840065C-25mg); 25 mg/mL (840065C-100mg)
• lipid type: cardiolipins; phospholipids
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: [H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CC)=O)COC(CCCCCCCCCCCCCCCCC)=O.[Na+]
• InChI: 1S/C46H78NO10P.Na/c1-3-5-7-9-11-13-15-17-19-20-21-22-24-26-28-30-32-34-36-38-45(49)57-42(40-55-58(52,53)56-41-43(47)46(50)51)39-54-44(48)37-35-33-31-29-27-25-23-18-16-14-12-10-8-6-4-2;/h5,7,11,13,17,19,21-22,26,28,32,34,42-43H,3-4,6,8-10,12,14-16,18,20,23-25,27,29-31,33,35-41,47H2,1-2H3,(H,50,51)(H,52,53);/q;+1/p-1/b7-5-,13-11-,19-17-,22-21-,28-26-,34-32-;/t42-,43+;/m1./s1
• InChI key: LANGJWMFDASXLA-OMTXNCIISA-M

Description

General description

In humans, phosphoserine (PS) is present in the endoplasmic reticulum, Golgi apparatus and grey matter. It is localized to the intracellular membranes, nuclear envelope, outer mitochondrial membranes, plasma membranes and myelin.

Application

18:0-22:6 PS or 1-stearoyl-2-docosahexaenoyl-sn-glycero-3-phospho-L-serine (sodium salt) has been used in liposome preparation to study effects of the fatty acid (FA) profile of phospholipids on membrane vesiculation by dynamin and endophilin.

Packaging

5 mL Clear Glass Sealed Ampule (840065C-100mg)

5 mL Clear Glass Sealed Ampule (840065C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• pictograms: GHS06,GHS08
• signalword: Danger
• hcodes: H302,H315,H319,H331,H336,H351,H361d,H372
• pcodes: P201 - P260 - P264 - P280 - P304 + P340 + P311 - P403 + P233
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• target_organs: Central nervous system
• Storage Class: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• wgk_germany: WGK 3
• flash_point_f: does not flash
• flash_point_c: does not flash