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810195P

Avanti

18:1-12:0 NBD PS

Avanti Research™ - A Croda Brand 810195P, powder

Synonym(s):

1-oleoyl-2-{12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl}-sn-glycero-3-phosphoserine (ammonium salt)

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About This Item

Empirical Formula (Hill Notation):
C42H73N6O13P
CAS Number:
474943-00-5
Molecular Weight:
901.04
MDL number:
MFCD00467278
UNSPSC Code:
12352211
NACRES:
NA.25

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 mg (810195P-1mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 810195P

shipped in

dry ice

storage temp.

−20°C

General description

Phosphatidylserine (PS) is an acidic membrane phospholipid present in human cerebral cortex.[1] It is majorly present in the inner leaflet of plasma membrane.[2] NBD PS contains the fluorophore, 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD) labelled at the headgroup of PS.[3]

Application

18:1-12:0 NBD PS or 1-oleoyl-2-{12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl}-sn-glycero-3-phosphoserine (ammonium salt), may be used to measure the phosphatidylserine decarboxylase (Psd1) activity.[4][5]

Biochem/physiol Actions

Phosphatidylserine (PS) is involved in maintaining the nerve cell membrane and myelin sheath.[6] Phosphatidylserine (PS) is associated with Akt, protein kinase C (PKC) and Raf-1 signaling.[1]

Packaging

5 mL Amber Glass Screw Cap Vial (810195P-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

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Organization and dynamics of N-(7-nitrobenz-2-oxa-1, 3-diazol-4-yl)-labeled lipids: a fluorescence approach
Mukherjee S, et al.
Chemistry and Physics of Lipids null
Structural Basis for Phosphatidylethanolamine Biosynthesis by Bacterial Phosphatidylserine Decarboxylase
Yasunori W, et al.
Structure null
Lipid Homeostasis Is Maintained by Dual Targeting of the Mitochondrial PE Biosynthesis Enzyme to the ER
Jonathan R, et al.
Developmental Cell null
Phosphatidylserine and the human brain
Glade MJ and Smith K
Nutrition null
Metabolism and functions of phosphatidylserine
Vance JE and Steenbergen R
Progress in Lipid Research null
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