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700009P

Avanti

15-ketocholestane

Avanti Research - A Croda Brand

Synonym(s):

3β-hydroxy-5α-cholestane-15-one

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About This Item

Empirical Formula (Hill Notation):
C27H46O2
CAS Number:
Molecular Weight:
402.65
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 5 mg (700009P-5mg)

manufacturer/tradename

Avanti Research - A Croda Brand

shipped in

dry ice

storage temp.

−20°C

General description

15-ketocholestane is the oxidized derivative of cholesterol[1] and is nonpolar lipid.[2]

Application

15-ketocholestane has been used as small molecule lipid to generate RAb2E9 recombinant monoclonal (RAb) using phage-library based screening).[3]

Biochem/physiol Actions

15-ketocholestane is a potential biomarker in multiple sclerosis and Autoimmune Encephalomyelitis (EAE).[3]

Packaging

5 mL Amber Glass Screw Cap Vial (700009P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids


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Novel phage display-derived mycolic acid-specific antibodies with potential for tuberculosis diagnosis
Chan CE, et al.
Journal of Lipid Research, 54(10), 2924-2932 (2013)
Antigen microarrays identify unique serum autoantibody signatures in clinical and pathologic subtypes of multiple sclerosis
Quintana FJ, et al.
Proceedings of the National Academy of Sciences of the USA, 105(48), 18889-18894 (2008)
Generation and characterization of a novel recombinant antibody against 15-ketocholestane isolated by phage-display
Islam MD, et al.
International Journal of Molecular Sciences, 13(4), 4937-4948 (2012)

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