QBD10819

MAL-dPEG^®₁₁-Lipoamide

• Synonym(s): Polyethylene glycol
• Empirical Formula (Hill Notation): C₃₉H₆₉N₃O₁₅S₂
• CAS Number: 1334172-73-4
• Molecular Weight: 884.11
• MDL number: MFCD21363248
• UNSPSC Code: 51171641
• PubChem Substance ID: 329823959
• NACRES: NA.22

Properties

• assay: >90%
• form: solid or viscous liquid
• reaction suitability: reagent type: chemical modification reagent; reagent type: cross-linking reagent; reactivity: gold reactive
• polymer architecture: shape: linear; functionality: heterobifunctional
• shipped in: ambient
• storage temp.: −20°C
• SMILES string: O=C(CCCCC1SSCC1)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCN2C(C=CC2=O)=O)=O
• InChI: 1S/C39H69N3O15S2/c43-36(4-2-1-3-35-8-34-58-59-35)40-9-12-47-14-16-49-18-20-51-22-24-53-26-28-55-30-32-57-33-31-56-29-27-54-25-23-52-21-19-50-17-15-48-13-10-41-37(44)7-11-42-38(45)5-6-39(42)46/h5-6,35H,1-4,7-34H2,(H,40,43)(H,41,44)
• InChI key: MCLHFRMIEQEYEN-UHFFFAOYSA-N

Description

Features and Benefits

MAL-dPEG^®₁₁-lipoamide is a crosslinker designed to allow crosslinking of a sulfhydryl-containing molecule with a metal surface such as gold or silver. The hydrophilic, non-immunogenic, single molecular weight dPEG^® spacer is 59.3 Å long, providing good separation between the target molecule and the metal surface. The spacer also increases the hydrodynamic volume of the conjugate and improves its water solubility. The maleimide function forms a thioether bond with a sulfhydryl group. One possible application of this product is immobilization of an antibody or antibody fragment onto a metal surface. Peptides and small molecules with free sulfhydryl groups could also be used in this way.

Legal Information

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable