QBD10289

m-dPEG^®₁₂-MAL

• Synonym(s): Polyethylene glycol
• Empirical Formula (Hill Notation): C₃₂H₅₈N₂O₁₅
• CAS Number: 88504-24-9
• Molecular Weight: 710.81
• MDL number: MFCD11041152
• UNSPSC Code: 51171641
• PubChem Substance ID: 329823909
• NACRES: NA.22

Properties

• assay: >90%
• form: solid or viscous liquid
• reaction suitability: reagent type: chemical modification reagent; reagent type: cross-linking reagent; reactivity: sulfhydryl reactive; reagent type: linker; reactivity: thiol reactive
• polymer architecture: shape: linear; functionality: monofunctional
• shipped in: ambient
• storage temp.: −20°C
• SMILES string: COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCN1C(C=CC1=O)=O)=O

Description

Features and Benefits

The m-dPEG^®₁₂-MAL provides a variety of means to modify small molecules, peptides, proteins, and functionalized surfaces (metals, glass, and others). The single molecular weight methoxy-terminated dPEG^® molecules are hydrophilic and non-immunogenic of exact length. Modification with m-dPEG^® reagents can improve water solubility, increase hydrodynamic volume, eliminate or reduce non-specific binding, protect peptides and proteins from proteolysis, reduce or eliminate immunogenicity, and increase serum half-life in vivo. The m-dPEG^®₁₂-MAL reacts with free sulfhydryls in a rapid, highly specific reaction in aqueous media at pH 6.5-7.5.

Legal Information

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable