P42053

3-Methylpyridine

99%

• Synonym(s): 3-Picoline, 3-Methylpyridine
• Empirical Formula (Hill Notation): C₆H₇N
• CAS Number: 108-99-6
• Molecular Weight: 93.13
• Beilstein/REAXYS Number: 1366
• EC Number: 203-636-9
• MDL number: MFCD00006402
• UNSPSC Code: 12352100
• PubChem Substance ID: 24898513
• NACRES: NA.22

Properties

• vapor density: 3.2 (vs air)
• vapor pressure: 4.4 mmHg ( 20 °C)
• assay: 99%
• autoignition temp.: ~1000 °F
• refractive index: n20/D 1.504 (lit.)
• bp: 144 °C (lit.)
• mp: −19 °C (lit.)
• density: 0.957 g/mL at 25 °C (lit.)
• SMILES string: Cc1cccnc1
• InChI: 1S/C6H7N/c1-6-3-2-4-7-5-6/h2-5H,1H3
• InChI key: ITQTTZVARXURQS-UHFFFAOYSA-N

Description

General description

3-methylpyridine acts as a nucleophile in cross-coupling reactions, enabling the formation of aryl-pyridine bonds and facilitating the synthesis of pyridine derivatives. It is used as a precursor in the synthesis of niacin (vitamin B3)

Application

• [The effect of new quaternary ammonium compounds on bacteria and fungi. 5: Synthesis of 3-methyl-n-alkylthiomethylpyridinium-, 1-methyl-3-n-alkylthiomethylimidazolium- and 1-ethyl-3-n-alkylthioimidazolinium chloride].: This research focuses on the synthesis of various quaternary ammonium compounds, including derivatives of 3-Methylpyridine, and evaluates their antimicrobial properties against bacteria and fungi (Pernak et al., 1983).
• Stereochemistry of cobalt porphyrins. I. The structure and characterization of 2,3,7,8,12,13,17,18-octaethylporphinatobis(3-methylpyridine)cobalt(II).: This paper discusses the synthesis, structural analysis, and stereochemical properties of cobalt porphyrins complexed with 3-Methylpyridine, highlighting their potential applications in catalysis and materials science (Little and Ibers, 1974).

Safety Information

• pictograms: GHS02,GHS06,GHS05
• signalword: Danger
• hcodes: H226,H302,H311 + H331,H314
• pcodes: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1B
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 1
• flash_point_f: 98.6 °F - closed cup
• flash_point_c: 37 °C - closed cup
• ppe: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter