M75608

2-Methylpyrazine

≥99%

• Synonym(s): 2-Methyl-1,4-diazine, Monomethylpyrazine
• Empirical Formula (Hill Notation): C₅H₆N₂
• CAS Number: 109-08-0
• Molecular Weight: 94.11
• Beilstein/REAXYS Number: 105778
• EC Number: 203-645-8
• MDL number: MFCD00006142
• UNSPSC Code: 12352100
• PubChem Substance ID: 24897016
• NACRES: NA.22

Properties

• assay: ≥99%
• form: liquid
• refractive index: n20/D 1.504 (lit.)
• bp: 135 °C/761 mmHg (lit.)
• mp: −29 °C (lit.)
• density: 1.03 g/mL at 25 °C (lit.)
• SMILES string: Cc1cnccn1
• InChI: 1S/C5H6N2/c1-5-4-6-2-3-7-5/h2-4H,1H3
• InChI key: CAWHJQAVHZEVTJ-UHFFFAOYSA-N

Description

General description

2-Methylpyrazine is an alkyl-substituted pyrazine used as a key intermediate in the synthesis of pyrazineamide, an anti-tubercular drug.

Application

2-Methylpyrazine can be used:

• As a ligand to prepare coordination polymer [Ag(CF₃CO₂)(2-Me-Pyz)], wherein 2-Me-Pyz is 2-methylpyrazine.
• To prepare 2-cyanopyrazine via ammoxidation reaction using MoVPO catalyst.
• As a ligand in the synthesis of fluorescent silver(I)-saccharinato complex, which exhibits blue luminescence at room temperature.

Safety Information

• pictograms: GHS02,GHS07
• signalword: Warning
• hcodes: H226,H302
• pcodes: P210 - P233 - P240 - P241 - P242 - P301 + P312
• Hazard Classifications: Acute Tox. 4 Oral - Flam. Liq. 3
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 3
• flash_point_f: 122.0 °F - closed cup
• flash_point_c: 50 °C - closed cup
• ppe: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter