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F11700

Sigma-Aldrich

Bis(4-fluoro-3-nitrophenyl) sulfone

97%

Synonym(s):

4,4′-Difluoro-3,3′-dinitrodiphenyl sulfone, 4-Fluoro-3-nitrophenyl sulfone

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About This Item

Linear Formula:
[FC6H3(NO2)]2SO2
CAS Number:
312-30-1
Molecular Weight:
344.25
Beilstein/REAXYS Number:
2486439
EC Number:
206-224-7
MDL number:
MFCD00007057
UNSPSC Code:
12352103

assay

97%

mp

191-194 °C (lit.)

SMILES string

[O-][N+](=O)c1cc(ccc1F)S(=O)(=O)c2ccc(F)c(c2)[N+]([O-])=O

InChI

1S/C12H6F2N2O6S/c13-9-3-1-7(5-11(9)15(17)18)23(21,22)8-2-4-10(14)12(6-8)16(19)20/h1-6H

InChI key

KHAWDEWNXJIVCJ-UHFFFAOYSA-N

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pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
20816DO
05123BI
04404EU
02304MO
00806TX

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W J Perkins et al.
The Journal of biological chemistry, 259(14), 8786-8793 (1984-07-25)
The fluorescent ADP analog, 1,N6-ethenoadenosine diphosphate (epsilon ADP), has been trapped at the active site of myosin subfragment 1 (SF1) by the chromophoric cross - linkers, 1,5 - difluoro - 2,4' - dinitrobenzene (F2DNB) and 4,4'-difluoro-3,3'-dinitrophenylsulfone (F2DPS). The cross-linking agents
W E Harris et al.
The Biochemical journal, 218(2), 331-339 (1984-03-01)
Interpeptide cross-linking of alpha-subunits with concomitant loss of Na+ + K+-transporting ATPase (Na+, K+-ATPase) activity was found when the purified lamb kidney enzyme was treated with the bifunctional thiol reagent 4,4'-difluoro-3,3'-dinitrodiphenyl sulphone (F2DNS). Several forms of the enzyme could be
J G Elferink et al.
Chemico-biological interactions, 52(2), 163-172 (1984-12-01)
The bifunctional fluorinated nitrobenzenes, 1,5-difluoro-2,4-dinitrobenzene (DFDNB) and 4,4'-difluoro-3,3'-dinitrodiphenyl sulfone (DFDNDPS), and the monofunctional 1-fluoro-2,4-dinitrobenzene (FDNB) inhibit chemotaxis, phagocytosis, exocytosis and the respiratory burst of rabbit polymorphonuclear leukocytes. Inhibition occurs in the micromolar concentration range; the bifunctional compounds are stronger inhibitory
N B Gusev et al.
Biochimica et biophysica acta, 626(1), 106-116 (1980-11-20)
In an attempt to detect Ca2+-induced conformational changes by crosslinking, rabbit muscle troponin complex was reacted with the bifunctional reagents 1,3-difluoro-4,6-dinitrobenzene, 4,4'-difluoro-3,3'-dinitrodiphenylsulfone and dimethyl suberimidate under various conditions and the products were analyzed by dodecyl sulfate gel electrophoresis. In the
Cross-linking of myosin subfragment 1. Nucleotide-enhanced modification by a variety of bifunctional reagents.
J A Wells et al.
The Journal of biological chemistry, 255(23), 11135-11140 (1980-12-10)
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