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D31206

Sigma-Aldrich

Dibenz[a,c]anthracene

97%

Synonym(s):

1,2:3,4-Dibenzanthracene

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100 MG
$114.00

About This Item

Empirical Formula (Hill Notation):
C22H14
CAS Number:
Molecular Weight:
278.35
Beilstein/REAXYS Number:
1912415
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

$114.00

List Price$120.00Save 5%
Web-Only Promotion

Available to ship onApril 21, 2025Details


Request a Bulk Order

Quality Level

assay

97%

form

powder

bp

518 °C (lit.)

mp

205-207 °C (lit.)

SMILES string

c1ccc2cc3c4ccccc4c5ccccc5c3cc2c1

InChI

1S/C22H14/c1-2-8-16-14-22-20-12-6-4-10-18(20)17-9-3-5-11-19(17)21(22)13-15(16)7-1/h1-14H

InChI key

RAASUWZPTOJQAY-UHFFFAOYSA-N

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Skull and crossbonesEnvironment

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Danger

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Acute 1

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


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I Chouroulinkov et al.
Cancer letters, 19(1), 21-26 (1983-05-01)
The tumor-initiating activities of dibenz[a,c]anthracene (DBA) and of the related trans-1,2-, 3,4- and 10,11-dihydrodiols have been examined on mouse skin subsequently promoted with 12-O-tetradecanoyl-phorbol-13-acetate (TPA). The 1,2- and 10,11-dihydrodiols were active and were more active than equivalent doses of either
Dibenz[a,c]anthracene.
IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans, 32, 289-297 (1983-12-01)
A Hewer et al.
Carcinogenesis, 2(12), 1345-1352 (1981-01-01)
In rat liver microsomal preparations, the 10,11-dihydrodiol of dibenz[a,c]anthracene (DBA) is metabolized to r-10,t-11-dihydroxy-t-12,13-oxy-10,11,12,13-tetrahydrodibenz[a,c]anthracene (anti-DBA 10,11-diol 12,13-oxide), the anti isomer of a non-bay-region diol-epoxide of DBA. When 3H-labelled DBA or trans-10,11-dihydro-10,11-dihydroxydibenz[a,c]anthracene were metabolized in this system in the presence of
M Hall et al.
Carcinogenesis, 9(5), 865-868 (1988-05-01)
Incubation of r-1,t-2-dihydroxy-t-3,4-oxy-1,2,3,4-tetrahydrochrysene (anti-chrysene-1,2-diol 3,4-oxide), the bay-region diol-epoxide of chrysene, with rat liver microsomes in the presence of NADP+ and DNA, followed by 32P-postlabelling analysis of the DNA, revealed the presence of at least two adducts not detected when anti-chrysene-1,2-diol
The metabolic activation of some polycyclic hydrocarbons: the role of dihydrodiols and diol-epoxides.
P Sims
Advances in experimental medicine and biology, 136 Pt A, 487-500 (1981-01-01)

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