D115207
6-Methyluracil
97%
Synonym(s):
2,4-Dihydroxy-6-methylpyrimidine
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assay
97%
form
powder
mp
318 °C (dec.) (lit.)
SMILES string
CC1=CC(=O)NC(=O)N1
InChI
1S/C5H6N2O2/c1-3-2-4(8)7-5(9)6-3/h2H,1H3,(H2,6,7,8,9)
InChI key
SHVCSCWHWMSGTE-UHFFFAOYSA-N
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Nucleosides, nucleotides & nucleic acids, 22(5-8), 1187-1189 (2003-10-21)
We synthesized pyrrolidino-C-nucleosides, incorporated them into oligodeoxynucleotides and investigated their pairing properties. The thermal duplex and triplex stabilities were measured. While triplex formation is destabilized in the case of pyrrolidino-pseudo-U and -T, pyrrolidino-pseudo-iso-C leads to an increase of the Tm
Bioorganic & medicinal chemistry letters, 13(19), 3317-3322 (2003-09-03)
A new class of small molecule GnRH antagonists, the 1-arylmethyl-3-(1-methyl-2-amino)ethyl-5-aryl-6-methyluracils, was designed and a novel stereoselective synthesis for these compounds was developed. The stereochemical integrities of key intermediates (S)-6 and (R)-6 were confirmed by a combination of X-ray crystallography and
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Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections, 399, 458-460 (2005-02-19)
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This paper reports the hydrothermal synthesis, experimental and theoretical studies of a novel cocrystal compound in the 2:1 stoichiometric ratio of 6-methyluracil (6mu) and dipicolinic acid (pydcH(2)) formulated as [6mu](2)[pydcH(2)] (1), for the first time. DFT calculations were performed to
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The reaction of K2PtCl4 with an excess of 1-methyluracilate (1-MeU) in water at 60 degrees C leads to the formation of two major products, K2[Pt(1-MeU-N3)4].10H2O (1) and trans-K[Pt(1-MeU-N3)2(1-MeU-C5)(H2O)].3H2O (2). Addition of CuCl2 to an aqueous solution of 2 yields the
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