A76400

3-Amino-1-propanol

99%

• Synonym(s): 3-Aminopropyl alcohol
• Linear Formula: HO(CH₂)₃NH₂
• CAS Number: 156-87-6
• Molecular Weight: 75.11
• Beilstein/REAXYS Number: 741855
• EC Number: 205-864-4
• MDL number: MFCD00008223
• UNSPSC Code: 12352100
• PubChem Substance ID: 24891263
• NACRES: NA.22

Properties

• vapor density: 2.59 (vs air)
• Quality Level: 200
• vapor pressure: 2.1 mmHg ( 20 °C)
• assay: 99%
• form: liquid
• autoignition temp.: 770 °F
• refractive index: n20/D 1.4598 (lit.)
• bp: 184-187 °C (lit.)
• mp: 10-12 °C (lit.)
• density: 0.982 g/mL at 20 °C (lit.)
• SMILES string: NCCCO
• InChI: 1S/C3H9NO/c4-2-1-3-5/h5H,1-4H2
• InChI key: WUGQZFFCHPXWKQ-UHFFFAOYSA-N

Description

General description

3-Amino-1-propanol is a linear primary alkanolamine.[1]

Application

3-Amino-1-propanol is often used as a molecular linker.[2][3] Generally, it can be used:

• In the preparation of polyurethanes[4] and poly(propyl ether imine) dendrimers.[5]
• As a key starting material in the total synthesis of (−)-ephedradine A[6] (orantine), (−)-and (+)-tedanalactam.[7]
• As a precursor to synthesize a variety of medicinally important compounds by selective O- or N-arylation and amidation of 3-amino-1-propanol.[8][9]

Safety Information

• pictograms: GHS05,GHS07
• signalword: Danger
• hcodes: H302,H314
• pcodes: P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B
• Storage Class: 8A - Combustible corrosive hazardous materials
• wgk_germany: WGK 1
• flash_point_f: 212.0 °F - Pensky-Martens closed cup
• flash_point_c: 100 °C - Pensky-Martens closed cup
• ppe: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter