Skip to Content
MilliporeSigma
All Photos(1)

Documents

935921

Sigma-Aldrich

Poly(glycerol sebacate)

Synonym(s):

PGS

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
[CH2CH(OH)CH2OOC(CH2)8COO]n
UNSPSC Code:
12352201
NACRES:
NA.21

form

solid

Quality Level

100

color

colorless to yellow

General description

Poly(glycerol sebacate) (PGS) is a biodegradable polymer with tunable mechanical properties that can be used in soft tissue engineering and regenerative medicine applications. It is non-immunogenic, non-cytotoxic and has minimal inflammatory response. The polymer backbone and crosslinks can undergo hydrolytic degradation due to the presence of ester linkages. The ester bonds in the polymer backbone covalently crosslink at high temperature (>130 °C) under vacuum without using any toxic crosslinkers to form a three-dimensional (3D) network of random coils.

Application

  • Scaffold material synthesis like blood vessels, cornea and nerve tissue
  • In orthopedic implants
  • In the drug delivery system and bioelectronic applications

Features and Benefits

  • Flexible elastomer with tunable mechanical properties
  • Higher reversible deformation properties
  • Shape memory
  • Bioresorbable polymer

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Synthesis, Characterization and 3D Micro-Structuring via 2-Photon Polymerization of Poly(glycerol sebacate)-Methacrylate?An Elastomeric Degradable Polymer
Tala, et al.
Frontiers in physics, 6, 41-41 (2018)
Poly(Glycerol Sebacate) in Biomedical Applications-A Review of the Recent Literature
Vogt L, et al.
Advanced Healthcare Materials, 10, e2002026-e2002026 (2021)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service