900584

5-Ethynyl-2′-deoxyuridine

95%

• Synonym(s): EdU
• Empirical Formula (Hill Notation): C₁₁H₁₂N₂O₅
• CAS Number: 61135-33-9
• Molecular Weight: 252.22
• UNSPSC Code: 12352208
• NACRES: NA.22

Properties

• Quality Level: 100
• assay: 95%
• form: powder
• mp: 206 °C
• storage temp.: −20°C
• SMILES string: OC[C@@H]1[C@@H](O)C[C@H](N2C(NC(C(C#C)=C2)=O)=O)O1
• InChI: 1S/C11H12N2O5/c1-2-6-4-13(11(17)12-10(6)16)9-3-7(15)8(5-14)18-9/h1,4,7-9,14-15H,3,5H2,(H,12,16,17)/t7-,8+,9+/m0/s1
• InChI key: CDEURGJCGCHYFH-DJLDLDEBSA-N

Description

General description

5-Ethynyl-2′-deoxyuridine (EdU) is a thymidine analogue that can be incorporated into cellular DNA for cell proliferation studies. The incorporated nucleoside analogue can be detected by a copper-catalyzed click reaction with a fluorescent azide.

Application

5-Ethynyl-2′-deoxyuridine (EdU) is used for:

• Labeling newly synthesized DNA during replication
• Cell proliferating assay studies
• Cell cycle analysis

For information on Baseclick kits containing all the reagents for the assays see: Baseclick kits

For a listing of the Baseclick kits see: Baseclick kits

Safety Information

• pictograms: GHS08
• signalword: Danger
• hcodes: H340,H361
• pcodes: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Muta. 1B - Repr. 2
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable