88717

(R)-1-[(S_P)-2-(Diphenylphosphino)ferrocenyl]ethyldicyclohexylphosphine

≥97%

• Synonym(s): (2R)-1-[(1R)-1-(Dicyclohexylphosphino)ethyl]-2-(diphenylphosphino)ferrocene (acc to CAS), (R)-(S)-Josiphos, Josiphos SL-J001-1
• Empirical Formula (Hill Notation): C₃₆H₄₄FeP₂ · C₂H₅OH
• CAS Number: 155806-35-2
• Molecular Weight: 640.60
• MDL number: MFCD00800284
• UNSPSC Code: 12352005
• PubChem Substance ID: 24888985
• NACRES: NA.22

Properties

• description: ethanol adduct
• Quality Level: 100
• assay: ≥97%
• form: powder
• optical purity: ee: ≥99%
• functional group: phosphine
• SMILES string: [Fe].[CH]1[CH][CH][CH][CH]1.C[C@H]([C]2[CH][CH][CH][C]2P(c3ccccc3)c4ccccc4)P(C5CCCCC5)C6CCCCC6
• InChI: 1S/C31H39P2.C5H5.Fe/c1-25(32(26-15-6-2-7-16-26)27-17-8-3-9-18-27)30-23-14-24-31(30)33(28-19-10-4-11-20-28)29-21-12-5-13-22-29;1-2-4-5-3-1;/h4-5,10-14,19-27H,2-3,6-9,15-18H2,1H3;1-5H;/t25-;;/m1../s1
• InChI key: HGTBZFMPHBAUCQ-KHZPMNTOSA-N

Description

General description

(R)-1-[(S_P)-2-(Diphenylphosphino)ferrocenyl]ethyldicyclohexylphosphine ((R,S)-josiphos) is a chiral ferrocenyl diphosphine ligand.[1]

sold in collaboration with Solvias AG

Application

It may be used in the preparation of cyclopentadienyliridium complexes, [IrCl(PP)]₂ and [IrCp(PP)]. (Cp= cyclopentadienyl; PP= (R)-1-[(S_P)-2-(diphenylphosphino)ferrocenyl]ethyldicyclohexylphosphine)[2]

Rhodium complex of (R)-(S)-JOSIPHOS can be used as a catalyst for the selective asymmetric hydrogenation of:       

• Z-β-aryl-β-(enamido)phosphonates.[3]     
•  o-alkoxy tetrasubstituted enamides to yield β-amino alcohol analogs with excellent enantiomeric excess.[4]

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)